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Descriptor English: Retinoblastoma
Descriptor Spanish: Retinoblastoma
Descriptor retinoblastoma
Entry term(s) glioblastoma retiniano
glioblastomas retinianos
glioma retiniano
gliomas retinianos
neuroblastoma retiniano
neuroblastomas retinianos
retinoblastoma esporádico
retinoblastoma familiar
retinoblastoma hereditario
retinoblastomas
retinoblastomas esporádicos
retinoblastomas familiares
retinoblastomas hereditarios
Scope note: Tumor maligno que surge de la capa nuclear de la retina. Es el tumor ocular primario más común en los niños. El tumor tiende a aparecer en la primera infancia o en lactantes y puede estar presente en el momento del nacimiento. La mayoría son esporádicos, pero la afección puede transmitirse como rasgo autosómico dominante. Histológicamente se caracteriza por celularidad densa, células redondas poligonales pequeñas y zonas de calcificación y necrosis. Las caracterísiticas clínicas más comunes son reflejo pupilar anormal (leucocoria), NISTAGMO, ESTRABISMO y afectación visual. (DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p. 2104)
Descriptor Portuguese: Retinoblastoma
Descriptor French: Rétinoblastome
Entry term(s): Cancer, Retinoblastoma Eye
Cancers, Retinoblastoma Eye
Eye Cancer, Retinoblastoma
Eye Cancers, Retinoblastoma
Familial Retinoblastoma
Familial Retinoblastomas
Glioblastoma, Retinal
Glioblastomas, Retinal
Glioma, Retinal
Gliomas, Retinal
Hereditary Retinoblastoma
Hereditary Retinoblastomas
Neuroblastoma, Retinal
Neuroblastomas, Retinal
Retinal Glioblastoma
Retinal Glioblastomas
Retinal Glioma
Retinal Gliomas
Retinal Neuroblastoma
Retinal Neuroblastomas
Retinoblastoma Eye Cancer
Retinoblastoma Eye Cancers
Retinoblastoma, Familial
Retinoblastoma, Hereditary
Retinoblastoma, Sporadic
Retinoblastomas
Retinoblastomas, Familial
Retinoblastomas, Hereditary
Retinoblastomas, Sporadic
Sporadic Retinoblastoma
Sporadic Retinoblastomas
Tree number(s): C04.557.465.625.600.725
C04.557.470.670.725
C04.557.580.625.600.725
C04.588.364.818.760
C11.270.862
C11.319.475.760
C11.768.717.760
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012175
Scope note: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
Annotation: coordinate IM with RETINAL NEOPLASMS (IM); /genetics: consider also GENES, RETINOBLASTOMA
Allowable Qualifiers: BL blood
BS blood supply
CF cerebrospinal fluid
CH chemistry
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SC secondary
SU surgery
TH therapy
UL ultrastructure
UR urine
VE veterinary
VI virology
Related: Genes, Retinoblastoma MeSH
DeCS ID: 12591
Unique ID: D012175
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/06/15
Retinoblastoma - Preferred
Concept UI M0018961
Scope note A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
Preferred term Retinoblastoma
Entry term(s) Cancer, Retinoblastoma Eye
Cancers, Retinoblastoma Eye
Eye Cancer, Retinoblastoma
Eye Cancers, Retinoblastoma
Glioblastoma, Retinal
Glioblastomas, Retinal
Glioma, Retinal
Gliomas, Retinal
Neuroblastoma, Retinal
Neuroblastomas, Retinal
Retinal Glioblastoma
Retinal Glioblastomas
Retinal Glioma
Retinal Gliomas
Retinal Neuroblastoma
Retinal Neuroblastomas
Retinoblastoma Eye Cancer
Retinoblastoma Eye Cancers
Retinoblastomas
Sporadic Retinoblastoma - Narrower
Concept UI M0336986
Preferred term Sporadic Retinoblastoma
Entry term(s) Retinoblastoma, Sporadic
Retinoblastomas, Sporadic
Sporadic Retinoblastomas
Familial Retinoblastoma - Narrower
Concept UI M0336985
Preferred term Familial Retinoblastoma
Entry term(s) Familial Retinoblastomas
Hereditary Retinoblastoma
Hereditary Retinoblastomas
Retinoblastoma, Familial
Retinoblastoma, Hereditary
Retinoblastomas, Familial
Retinoblastomas, Hereditary



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