Descriptor English: | Genes, Retinoblastoma | ||||||
Descriptor Spanish: |
Genes de Retinoblastoma
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Descriptor Portuguese: | Genes do Retinoblastoma | ||||||
Descriptor French: | Gènes du rétinoblastome | ||||||
Entry term(s): |
Gene, Rb Gene, Retinoblastoma Genes, Rb Rb Gene Rb Genes Retinoblastoma Gene Retinoblastoma Genes |
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Tree number(s): |
G05.360.340.024.340.375.249.400 G05.360.340.024.340.415.400.400 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D016161 | ||||||
Scope note: | Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma. |
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Allowable Qualifiers: |
DE drug effects ES ethics GE genetics IM immunology PH physiology RE radiation effects |
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Previous Indexing: |
Retinoblastoma/genetics (1972-1990) |
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Public MeSH Note: | 91 |
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History Note: | 91 |
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Related: |
Retinoblastoma
MeSH | ||||||
DeCS ID: | 28960 | ||||||
Unique ID: | D016161 | ||||||
NLM Classification: | QZ 210 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1991/01/01 | ||||||
Date of Entry: | 1990/05/07 | ||||||
Revision Date: | 2010/06/25 |
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PHENOMENA AND PROCESSES
Genetic Phenomena [G05]Genetic Phenomena -
PHENOMENA AND PROCESSES
Genetic Phenomena [G05]Genetic Phenomena
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Genes, Retinoblastoma
- Preferred
Concept UI |
M0024674 |
Scope note | Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma. |
Preferred term | Genes, Retinoblastoma |
Entry term(s) |
Gene, Rb Gene, Retinoblastoma Genes, Rb Rb Gene Rb Genes Retinoblastoma Gene Retinoblastoma Genes |
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