DeCS

Descriptor English:

Shwartzman Phenomenon

Descriptor Spanish:

Fenómeno de Shwartzman

Spanish from Spain

Descriptor	fenómeno de Shwartzman
Entry term(s)	fenómeno de Schwartzman reacción de Shwartzman
Scope note:	Necrosis hemorrágica, demostrada por vez primera en conejos, como reacción en dos etapas: una inicial con inyección local (intradérmica) o general (intravenosa) de una endotoxina cebadora (ENDOTOXINAS), seguida de una segunda inyección intravenosa de endotoxina (agente provocador) a las 24 horas. Se produjo una inflamación aguda con daños en los vasos sanguíneos de pequeño tamaño. La subsiguiente coagulación intravascular provocó TROMBOSIS y NECROSIS en capilares y venas. El fenómeno de Shwartzman también puede provocarse en otras especies con una única inyección de agente provocador, y durante infecciones y en la gestación. La susceptibilidad depende del estado del SISTEMA INMUNOLÓGICO, coagulación, FIBRINOLISIS y flujo sanguíneo.

Descriptor Portuguese:

Fenômeno de Shwartzman

Descriptor French:

Réaction de Schwartzman

Entry term(s):

Phenomenon, Schwartzman
Phenomenon, Shwartzman
Schwartzman Phenomenon
Schwartzman Reaction
Schwartzman Reactions
Shwartzman Reaction

Tree number(s):

C14.907.454.810
C14.907.940.890
C15.378.463.515.810

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D012790

Scope note:

Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.

Allowable Qualifiers:

BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology

Concept UI	M0019807
Scope note	Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow.
Preferred term	Shwartzman Phenomenon
Entry term(s)	Phenomenon, Schwartzman Phenomenon, Shwartzman Schwartzman Phenomenon Schwartzman Reaction Schwartzman Reactions Shwartzman Reaction

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