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Descriptor English: Aurovertins
Descriptor Spanish: Aurovertinas
Descriptor aurovertinas
Scope note: Derivados complejos de pironas, muy tóxicos, que se obtienen del hongo Calcarisporium arbuscula. Se unen a la ATPasa mitocondrial y la inhiben, desacoplando la fosforilación oxidativa. Se utilizan como herramientas bioquímicas.
Descriptor Portuguese: Aurovertinas
Descriptor French: Aurovertine
Entry term(s): Aurovertin
Tree number(s): D03.383.663.075
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001313
Scope note: Very toxic and complex pyrone derivatives from the fungus Calcarisporium arbuscula. They bind to and inhibit mitochondrial ATPase, thereby uncoupling oxidative phosphorylation. They are used as biochemical tools.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Indicators and Reagents
Uncoupling Agents
Previous Indexing: Antibiotics (1968-1974)
Public MeSH Note: 91; was see under PYRANS 1980-90; was AUROVERTIN see under ANTIBIOTICS 1975-79
Online Note: use AUROVERTINS to search AUROVERTIN 1975-79
History Note: 91(80); was see under PYRANS 1980-90; was AUROVERTIN see under ANTIBIOTICS 1975-79
DeCS ID: 1319
Unique ID: D001313
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/27
Aurovertins - Preferred
Concept UI M0001976
Scope note Very toxic and complex pyrone derivatives from the fungus Calcarisporium arbuscula. They bind to and inhibit mitochondrial ATPase, thereby uncoupling oxidative phosphorylation. They are used as biochemical tools.
Preferred term Aurovertins
Entry term(s) Aurovertin



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