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Descriptor English: Glaucarubin
Descriptor Spanish: Glaucarrubina
Descriptor glaucarrubina
Entry term(s) kirondrina
Scope note: (1 beta,2 alfa,11 beta,12 alfa,15 beta(S))-11,20-epoxi-1,2,11,12-tetrahidroxi-15-(2-hidroxi-2-metil-1-oxobutoxi)picras-3-en-16-ona. Quasinoide (simaroubolido) de Simaruba glauca, un arbusto tropical. Se ha utilizado como antiamebiano y se ha observado que es citotóxico. Puede utilizarse en la quimioterapia frente al cáncer.
Descriptor Portuguese: Glaucarubina
Descriptor French: Glaucarubine
Entry term(s): Kirondrin
Tree number(s): D02.455.849.919.570.500
D03.383.663.387
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005900
Scope note: (1 beta,2 alpha,11 beta,12 alpha,15 beta(S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Phytogenic
Registry Number: EH6H7VS52J
CAS Type 1 Name: Picras-3-en-16-one, 11,20-epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)-, (1beta,2alpha,11beta,12alpha,15beta(S))-
Public MeSH Note: 91; was see under PHENANTHRENES 1981-90; was see under PYRANS 1975-80
History Note: 91(66); was see under PHENANTHRENES 1981-90; was see under PYRANS 1975-80
DeCS ID: 6040
Unique ID: D005900
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Glaucarubin - Preferred
Concept UI M0009259
Scope note (1 beta,2 alpha,11 beta,12 alpha,15 beta(S))-11,20-Epoxy-1,2,11,12-tetrahydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)picras-3-en-16-one. A quassinoid (Simaroubolide) from Simaruba glauca, a tropical shrub. It has been used as an antiamebic agent and is found to be cytotoxic. It may be of use in cancer chemotherapy.
Preferred term Glaucarubin
Entry term(s) Kirondrin



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