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Descriptor English: Spermine Synthase
Descriptor Spanish: Espermina Sintasa
Descriptor espermina sintasa
Entry term(s) espermina sintetasa
Scope note: Enzima que cataliza la transferencia de la parte propilamina de la 5'-desoxi-5'-S-(3-metiltiopropilamina)sulfonio adenosina a la espermidina, en la biosíntesis de espermina. Tiene un punto isoeléctrico acídico a pH 5,0. EC 2.5.1.22.
Descriptor Portuguese: Espermina Sintase
Descriptor French: Spermine synthase
Entry term(s): Aminopropyltransferase, Spermidine
Spermidine Aminopropyltransferase
Spermine Synthetase
Synthase, Spermine
Synthetase, Spermine
Tree number(s): D08.811.913.225.912
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013097
Scope note: An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to spermidine in the biosynthesis of spermine. It has an acidic isoelectric point at pH 5.0. EC 2.5.1.22.
Annotation: do not confuse with SPERMIDINE SYNTHASE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.5.1.22
CAS Type 1 Name: S-Adenosylmethioninamine:spermidine 3-aminopropyltransferase
Previous Indexing: Propylamines (1972-1974)
Spermine (1972-1974)
Transferases (1972-1974)
Public MeSH Note: 91; was see under TRANSFERASES 1975-90
History Note: 91(75); was see under TRANSFERASES 1975-90
DeCS ID: 13480
Unique ID: D013097
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2003/07/09
Spermine Synthase - Preferred
Concept UI M0020289
Scope note An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to spermidine in the biosynthesis of spermine. It has an acidic isoelectric point at pH 5.0. EC 2.5.1.22.
Preferred term Spermine Synthase
Entry term(s) Aminopropyltransferase, Spermidine
Spermidine Aminopropyltransferase
Spermine Synthetase
Synthase, Spermine
Synthetase, Spermine



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