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Descriptor English: Dimethylallyltranstransferase
Descriptor Spanish: Dimetilaliltranstransferasa
Descriptor dimetilaliltranstransferasa
Entry term(s) dimetilaliltransferasa
geranilpirofosfato sintetasa
preniltransferasa
Scope note: Enzima que, en la vía de la biosíntesis del colesterol, cataliza la condensación de isopentenil pirofosfato y dimetilalilpirofosfato para formar pirofosfato y geranilpirofosfato. La enzima entonces cataliza la condensación de este último compuesto con otra molécula de isopentenil pirofosfato, dando lugar a pirofosfato y farnesilpirofosfato. EC 2.5.1.1.
Descriptor Portuguese: Dimetilaliltranstransferase
Descriptor French: Dimethylallyltransferase
Entry term(s): Dimethylallyltransferase
Dolichyl Phosphate Synthetase
Geranylgeranyl Pyrophosphate Synthetase
Geranylpyrophosphate Synthetase
Nerylpyrophosphate Synthetase
Prenyltransferase
Synthetase, Geranylpyrophosphate
Synthetase, Nerylpyrophosphate
Tree number(s): D08.811.913.225.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004122
Scope note: An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.5.1.1
CAS Type 1 Name: Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyl (trans) transferase
Previous Indexing: Allyl Compounds (1971-1978)
Transferases (1966-1978)
Public MeSH Note: 97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90)
History Note: 97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90)
DeCS ID: 4170
Unique ID: D004122
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1978/05/18
Revision Date: 2014/06/13
Dimethylallyltranstransferase - Preferred
Concept UI M0006457
Scope note An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.
Preferred term Dimethylallyltranstransferase
Entry term(s) Dimethylallyltransferase
Dolichyl Phosphate Synthetase
Geranylpyrophosphate Synthetase
Nerylpyrophosphate Synthetase
Prenyltransferase
Synthetase, Geranylpyrophosphate
Synthetase, Nerylpyrophosphate
Geranylgeranyl Pyrophosphate Synthetase - Related but not broader or narrower
Concept UI M0588256
Preferred term Geranylgeranyl Pyrophosphate Synthetase



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