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Descriptor English: Succinate-CoA Ligases
Descriptor Spanish: Succinato-CoA Ligasas
Descriptor succinato-CoA ligasas
Entry term(s) succinato tiocinasas
succinato-CoA ligasa (formadora de ADP)
succinato-CoA ligasa (formadora de GDP)
succinato-CoA-ligasa
succinil CoA sintetasas
succinil coenzima A sintetasas
succinil-CoA-sintetasa
succinil-coenzima A-sintetasa
succínico-tiocinasa
Scope note: Enzimas que catalizan el primer paso de la oxidación del ácido succínico mediante la formación reversible de succinil-CoA a partir de succinato y CoA, con desdoblamiento concomitante del ATP a ADP (EC 6.2.1.5) o GTP a GDP (EC 6.2.1.4) y ortofosfato. El itaconato puede actuar en lugar del succinato y el ITP en vez del GTP. EC 6.2.1.-.
Descriptor Portuguese: Succinato-CoA Ligases
Descriptor French: Succinate-coA ligases
Entry term(s): CoA Synthetase, Succinyl
CoA Synthetases, Succinyl
Ligase, Succinate-CoA
Ligases, Succinate-CoA
Succinate CoA Ligase
Succinate CoA Ligases
Succinate-CoA Ligase
Succinate-CoA Ligase (GDP-Forming)
Succinate-CoA Ligases (ADP-Forming)
Succinic Thiokinase
Succinic Thiokinases
Succinyl CoA Synthetase
Succinyl CoA Synthetases
Succinyl Coenzyme A Synthetase
Succinyl Coenzyme A Synthetases
Synthetase, Succinyl CoA
Synthetases, Succinyl CoA
Thiokinase, Succinic
Thiokinases, Succinic
Tree number(s): D08.811.464.267.500.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013389
Scope note: Enzymes that catalyze the first step leading to the oxidation of succinic acid by the reversible formation of succinyl-CoA from succinate and CoA with the concomitant cleavage of ATP to ADP (EC 6.2.1.5) or GTP to GDP (EC 6.2.1.4) and orthophosphate. Itaconate can act instead of succinate and ITP instead of GTP.EC 6.2.1.-.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.2.1.-
CAS Type 1 Name: Succinate:CoA ligase (GDP- or ADP-forming)
Previous Indexing: Coenzyme A Synthetases (1973)
Succinates (1973)
Public MeSH Note: 98; see SUCCINYL COENZYME A SYNTHETASES 1991-97; see COENZYME A SYNTHETASES 1976-90
History Note: 98(76)
DeCS ID: 13775
Unique ID: D013389
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/07/25
Revision Date: 2020/05/27
Succinate-CoA Ligases - Preferred
Concept UI M0020708
Scope note Enzymes that catalyze the first step leading to the oxidation of succinic acid by the reversible formation of succinyl-CoA from succinate and CoA with the concomitant cleavage of ATP to ADP (EC 6.2.1.5) or GTP to GDP (EC 6.2.1.4) and orthophosphate. Itaconate can act instead of succinate and ITP instead of GTP.EC 6.2.1.-.
Preferred term Succinate-CoA Ligases
Entry term(s) CoA Synthetase, Succinyl
CoA Synthetases, Succinyl
Ligase, Succinate-CoA
Ligases, Succinate-CoA
Succinate CoA Ligase
Succinate CoA Ligases
Succinate-CoA Ligase
Succinic Thiokinase
Succinic Thiokinases
Succinyl CoA Synthetase
Succinyl CoA Synthetases
Succinyl Coenzyme A Synthetase
Succinyl Coenzyme A Synthetases
Synthetase, Succinyl CoA
Synthetases, Succinyl CoA
Thiokinase, Succinic
Thiokinases, Succinic
Succinate-CoA Ligase (GDP-Forming) - Narrower
Concept UI M0020709
Preferred term Succinate-CoA Ligase (GDP-Forming)
Succinate-CoA Ligases (ADP-Forming) - Narrower
Concept UI M0020710
Preferred term Succinate-CoA Ligases (ADP-Forming)



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