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Descriptor English: Azacosterol
Descriptor Spanish: Azacosterol
Descriptor azacosterol
Entry term(s) 20,25-diazacolesterol
azacolesterol
Scope note: Derivado diazídico del colesterol que actúa como hipocolesterolemiante inhibiendo a la delta-24-reductasa, que causa la acumulación de desmosterol.
Descriptor Portuguese: Azacosterol
Descriptor French: Azacostérol
Entry term(s): 20,25 Diazacholesterol
20,25-Diazacholesterol
Diazacholesterol Dihydrochloride
Dihydrochloride, Diazacholesterol
SC 12937
Tree number(s): D04.210.500.247.222.284.070
D04.210.500.247.808.197.070
D10.570.938.208.070
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001373
Scope note: Diaza derivative of cholesterol which acts as a hypocholesteremic agent by blocking delta-24-reductase, which causes the accumulation of desmosterol.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticholesteremic Agents
Registry Number: EPT876J73A
CAS Type 1 Name: Androst-5-en-3-ol, 17-((3-(dimethylamino)propyl)methylamino)-, (3beta,17beta)-
Previous Indexing: Aza Compounds (1972-1977)
Cholesterol (1966-1977)
Public MeSH Note: 91; was see under CHOLESTEROL 1978-90
History Note: 91(78); was see under CHOLESTEROL 1978-90
DeCS ID: 1385
Unique ID: D001373
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/15
Revision Date: 2016/07/01
Azacosterol - Preferred
Concept UI M0002057
Scope note Diaza derivative of cholesterol which acts as a hypocholesteremic agent by blocking delta-24-reductase, which causes the accumulation of desmosterol.
Preferred term Azacosterol
Entry term(s) 20,25 Diazacholesterol
20,25-Diazacholesterol
Diazacholesterol Dihydrochloride - Narrower
Concept UI M0002059
Preferred term Diazacholesterol Dihydrochloride
Entry term(s) Dihydrochloride, Diazacholesterol
SC 12937 - Narrower
Concept UI M0002058
Preferred term SC 12937



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