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Descriptor English:

Tamoxifen

Descriptor Spanish:

Tamoxifeno

Spanish from Spain

Descriptor	tamoxifeno
Entry term(s)	ICI-46474
Scope note:	Uno de los MODULADORES SELECTIVOS DE LOS RECEPTORES DE ESTRÓGENO con actividades específicas de los tejidos. El tamoxifeno actúa como antiestrógeno (agente inhibidor) en el tejido mamario, pero como estrógeno (agente estimulador) en el metabolismo del colesterol, densidad ósea y proliferación celular en el ENDOMETRIO.

Descriptor Portuguese:

Tamoxifeno

Descriptor French:

Tamoxifène

Entry term(s):

Citrate de tamoxifène
ICI-46,474
ICI-46474
ICI-47699
ICI46,474
ICI46474
ICI47699

Tree number(s):

D02.455.426.559.389.150.700.900

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D013629

Scope note:

One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Estrogen Antagonists
Antineoplastic Agents, Hormonal
Selective Estrogen Receptor Modulators
Bone Density Conservation Agents

Registry Number:

094ZI81Y45

CAS Type 1 Name:

Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-

DeCS ID:

14010

Unique ID:

D013629

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents