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Descriptor English: Tryptophan Synthase
Descriptor Spanish: Triptófano Sintasa
Descriptor triptófano sintasa
Entry term(s) triptófano sintetasa
Scope note: Enzima que cataliza la conversión de L-serina y 1-(indol-3-il)glicerol 3-fosfato en L-triptofano y gliceraldehído 3-fosfato. Es una proteína que requiere fosfato de piridoxal y cataliza la conversión de serina e indol en triptofano y agua y del indolglicerol fosfato en indol y gliceraldehído fosfato. (Enzyme Nomenclature, 1992) EC 4.2.1.20.
Descriptor Portuguese: Triptofano Sintase
Descriptor French: Tryptophan synthase
Entry term(s): Synthase, Tryptophan
Synthetase, Tryptophan
Tryptophan Synthetase
Tree number(s): D08.811.520.241.300.850
D08.811.600.896
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014367
Scope note: An enzyme that catalyzes the conversion of L-serine and 1-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyzes the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. (From Enzyme Nomenclature, 1992) EC 4.2.1.20.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 4.2.1.20
CAS Type 1 Name: L-Serine hydro-lyase (adding indoleglycerol-phosphate)
Previous Indexing: Hydro-Lyases (1966-1971)
Public MeSH Note: 80; was TRYPTOPHAN SYNTHETASE 1974-79
Online Note: use TRYPTOPHAN SYNTHASE to search TRYPTOPHAN SYNTHETASE 1972-79 (as Prov 1972-73)
History Note: 80; was TRYPTOPHAN SYNTHETASE 1972-79 (Prov 1972-73)
DeCS ID: 14769
Unique ID: D014367
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2003/07/09
Tryptophan Synthase - Preferred
Concept UI M0022092
Scope note An enzyme that catalyzes the conversion of L-serine and 1-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyzes the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. (From Enzyme Nomenclature, 1992) EC 4.2.1.20.
Preferred term Tryptophan Synthase
Entry term(s) Synthase, Tryptophan
Synthetase, Tryptophan
Tryptophan Synthetase



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