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Descriptor English: Bleomycin
Descriptor Spanish: Bleomicina
Descriptor bleomicina
Scope note: Complejo de antibióticos glicopeptídicos relacionados obtenidos de Streptomyces verticillus, constituído por bleomicina A2 y B2. Inhibe el metabolismo del ADN y se utiliza como antineoplásico, especialmente en tumores sólidos.
Descriptor Portuguese: Bleomicina
Descriptor French: Bléomycine
Entry term(s): Bléomycines
Sulfate de bléomycine
Tree number(s): D09.400.420.110
D12.644.233.110
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001761
Scope note: A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.
Annotation: a glycopeptide antineoplastic antibiotic
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antibiotics, Antineoplastic
Registry Number: 11056-06-7
DeCS ID: 1786
Unique ID: D001761
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05
Bléomycine - Preferred
Concept UI M0002657
Preferred term Bléomycine
Entry term(s) Bléomycines
Sulfate de bléomycine - Narrower
Concept UI M0330861
Preferred term Sulfate de bléomycine



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