| Descriptor English: | Arachidonate 5-Lipoxygenase | ||||||
| Descriptor Spanish: |
Araquidonato 5-Lipooxigenasa
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| Descriptor Portuguese: | Araquidonato 5-Lipoxigenase | ||||||
| Descriptor French: | Arachidonate 5-lipoxygenase | ||||||
| Entry term(s): |
5 Lipoxygenase 5-Lipoxygenase 5-Lipoxygenase, Arachidonate 5-Lipoxygenase, Arachidonic Acid Arachidonate 5 Lipoxygenase Arachidonic Acid 5 Lipoxygenase Arachidonic Acid 5-Lipoxygenase LTA4 Synthase Leukotriene A Synthase Leukotriene A4 Synthase Leukotriene A4 Synthetase Synthase, LTA4 Synthase, Leukotriene A Synthase, Leukotriene A4 Synthetase, Leukotriene A4 |
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| Tree number(s): |
D08.811.682.690.416.583.500.055 D12.776.556.579.374.568.500.020 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D001094 | ||||||
| Scope note: | An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
antagonists & inhibitors:Lipoxygenase Inhibitors
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| Registry Number: | EC 1.13.11.34 | ||||||
| CAS Type 1 Name: | Arachidonate:oxygen 5-oxidoreductase | ||||||
| Previous Indexing: |
Lipoxygenases (1974-1986) Oxygenases (1966-1973) |
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| Public MeSH Note: | 91; was see under ARACHIDONATE LIPOXYGENASES 1987-90 |
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| History Note: | 91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90 |
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| DeCS ID: | 19074 | ||||||
| Unique ID: | D001094 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1986/06/16 | ||||||
| Revision Date: | 2010/06/25 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Arachidonate 5-Lipoxygenase
- Preferred
| Concept UI |
M0001648 |
| Scope note | An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes. |
| Preferred term | Arachidonate 5-Lipoxygenase |
| Entry term(s) |
5 Lipoxygenase 5-Lipoxygenase 5-Lipoxygenase, Arachidonate 5-Lipoxygenase, Arachidonic Acid Arachidonate 5 Lipoxygenase Arachidonic Acid 5 Lipoxygenase Arachidonic Acid 5-Lipoxygenase LTA4 Synthase Leukotriene A Synthase Leukotriene A4 Synthase Leukotriene A4 Synthetase Synthase, LTA4 Synthase, Leukotriene A Synthase, Leukotriene A4 Synthetase, Leukotriene A4 |
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