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Descriptor English: Arachidonate 15-Lipoxygenase
Descriptor Spanish: Araquidonato 15-Lipooxigenasa
Descriptor araquidonato 15-lipooxigenasa
Entry term(s) 15-lipooxigenasa
Scope note: Enzima que cataliza la oxidación del ácido araquidónico para formar 15-hidroperoxiaraquidonato (15-HPETE), que es convertido rápidamente en 15-hidroxi-5,8,11,13-eicosatetraenoato (15-HETE). Los 15-hidroxiperóxidos se forman preferentemente en los neutrófilos y linfocitos. EC 1.13.11.33.
Descriptor Portuguese: Araquidonato 15-Lipoxigenase
Descriptor French: Arachidonate 15-lipoxygenase
Entry term(s): 15 Lipoxygenase
15-Lipoxygenase
15-Lipoxygenase, Arachidonate
15-Lipoxygenase, Arachidonic Acid
Arachidonate 15 Lipoxygenase
Arachidonic Acid 15 Lipoxygenase
Arachidonic Acid 15-Lipoxygenase
Tree number(s): D08.811.682.690.416.583.500.065
D12.776.556.579.374.568.500.030
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001093
Scope note: An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Lipoxygenase Inhibitors
Registry Number: EC 1.13.11.33
CAS Type 1 Name: Arachidonate:oxygen 15-oxidoreductase
Previous Indexing: Lipoxygenases (1974-1986)
Oxygenases (1966-1973)
Public MeSH Note: 91; was see under ARACHIDONATE LIPOXYGENASES 1987-90
History Note: 91(87); was see under ARACHIDONATE LIPOXYGENASES 1987-90
DeCS ID: 19076
Unique ID: D001093
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1986/06/16
Revision Date: 2010/06/25
Arachidonate 15-Lipoxygenase - Preferred
Concept UI M0001647
Scope note An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.
Preferred term Arachidonate 15-Lipoxygenase
Entry term(s) 15 Lipoxygenase
15-Lipoxygenase
15-Lipoxygenase, Arachidonate
15-Lipoxygenase, Arachidonic Acid
Arachidonate 15 Lipoxygenase
Arachidonic Acid 15 Lipoxygenase
Arachidonic Acid 15-Lipoxygenase



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