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Descriptor English: Arachidonate Lipoxygenases
Descriptor Spanish: Araquidonato Lipooxigenasas
Descriptor araquidonato lipooxigenasas
Scope note: Enzimas que catalizan la oxidación del ácido araquidónico a hidroperoxiaraquidonatos (HPETES). Estos productos son entonces rápidamente convertidos por una peroxidasa en ácidos hidroxieicosatetraenóicos (HETES). La especificidad posicional de la reacción enzimática varía de unos tejidos a otros. La vía final de la lipoxigenasa conduce a los leucotrienos. EC 1.13.11.-.
Descriptor Portuguese: Araquidonato Lipoxigenases
Descriptor French: Arachidonate lipoxygenases
Entry term(s): Arachidonic Acid Lipoxygenase
Lipoxygenase, Arachidonic Acid
Lipoxygenases, Arachidonate
Tree number(s): D08.811.682.690.416.583.500
D12.776.556.579.374.568.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001091
Scope note: Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates. These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids. The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. EC 1.13.11.- .
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.13.11.-
Previous Indexing: Lipoxygenases (1974-1986)
Oxygenases (1966-1973)
Public MeSH Note: 87
History Note: 87
DeCS ID: 19077
Unique ID: D001091
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1986/06/16
Revision Date: 2010/06/25
Arachidonate Lipoxygenases - Preferred
Concept UI M0001645
Scope note Enzymes catalyzing the oxidation of arachidonic acid to hydroperoxyarachidonates. These products are then rapidly converted by a peroxidase to hydroxyeicosatetraenoic acids. The positional specificity of the enzyme reaction varies from tissue to tissue. The final lipoxygenase pathway leads to the leukotrienes. EC 1.13.11.- .
Preferred term Arachidonate Lipoxygenases
Entry term(s) Arachidonic Acid Lipoxygenase
Lipoxygenase, Arachidonic Acid
Lipoxygenases, Arachidonate



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