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Descriptor English: Midazolam
Descriptor Spanish: Midazolam
Descriptor midazolam
Scope note: Compuesto hipnótico-sedante de acción rápida, con propiedades ansiolíticas y amnésicas. Se utiliza en odontología, cirugía cardíaca, procedimientos endoscópicos, como medicación preanestésica y como coadyuvante en anestesia local. Debido a su corta duración y estabilidad cardiorrespiratoria, es particularmente útil en pacientes de riesgo, ancianos y cardíacos. Se trata de un compuesto hidrosoluble a pH inferiores a 4, y liposoluble a pH fisiológico.
Descriptor Portuguese: Midazolam
Descriptor French: Midazolam
Entry term(s): Dormicum
Hydrochloride, Midazolam
Maleate, Midazolam
Midazolam Hydrochloride
Midazolam Maleate
Ro 21 3981
Ro 21-3981
Ro 213981
Versed
Tree number(s): D03.633.100.079.080.575
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008874
Scope note: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Adjuvants, Anesthesia
Hypnotics and Sedatives
Anti-Anxiety Agents
Anesthetics, Intravenous
GABA Modulators
Registry Number: R60L0SM5BC
CAS Type 1 Name: 4H-Imidazo(1,5-a)(1,4)benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-
Previous Indexing: Azepines (1966-1974)
Benzodiazepines (1975-1986)
Public MeSH Note: 87
History Note: 87
DeCS ID: 19248
Unique ID: D008874
NLM Classification: QV 85
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1986/04/09
Revision Date: 2016/05/31
Midazolam - Preferred
Concept UI M0013843
Scope note A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
Preferred term Midazolam
Midazolam Maleate - Narrower
Concept UI M0013846
Preferred term Midazolam Maleate
Entry term(s) Maleate, Midazolam
Dormicum - Narrower
Concept UI M0013842
Preferred term Dormicum
Versed - Narrower
Concept UI M0013845
Preferred term Versed
Midazolam Hydrochloride - Narrower
Concept UI M0353521
Preferred term Midazolam Hydrochloride
Entry term(s) Hydrochloride, Midazolam
Ro 21-3981 - Narrower
Concept UI M0013844
Preferred term Ro 21-3981
Entry term(s) Ro 21 3981
Ro 213981



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