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Descriptor English: DNA, Superhelical
Descriptor Spanish: ADN Superhelicoidal
Descriptor ADN superhelicoidal
Entry term(s) ADN superenrollado
ADN superespiral
Scope note: ADN bicatenario circular, de forma superenrollada, que se ha aislado de virus, bacterias y mitocondrias. Es rico en energía libre. Durante la transcripción, la magnitud de la iniciación del ARN es proporcional al carácter superhelicoidal del ADN.
Descriptor Portuguese: DNA Super-Helicoidal
Descriptor French: ADN superhélicoïdal
Entry term(s): DNA, Supercoiled
DNA, Supertwisted
Supercoiled DNA
Superhelical DNA
Supertwisted DNA
Tree number(s): D13.444.308.283.250
G02.111.570.820.486.212.250
G05.360.580.156.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004278
Scope note: Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity.
Annotation: IM; /drug eff /ultrastruct permitted
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA (1966-1977)
DNA, Circular (1973-1977)
Public MeSH Note: 78
History Note: 78
DeCS ID: 22162
Unique ID: D004278
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1977/05/17
Revision Date: 2015/06/22
DNA, Superhelical - Preferred
Concept UI M0006694
Scope note Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity.
Preferred term DNA, Superhelical
Entry term(s) DNA, Supercoiled
DNA, Supertwisted
Supercoiled DNA
Superhelical DNA
Supertwisted DNA



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