| Descriptor English: | Immunoglobulins |
| Descriptor Spanish: | Inmunoglobulinas |
| Descriptor Portuguese: | Imunoglobulinas |
| Descriptor French: | Immunoglobulines |
| Entry term(s): |
Globulin, Immune Globulins, Immune Immune Globulin Immune Globulins Immunoglobulin |
| Tree number(s): |
D12.776.124.486.485 D12.776.124.790.651 D12.776.377.715.548 |
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D007136 |
| Scope note: | Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. |
| Annotation: | general: prefer specifics; /admin: consider also IMMUNOGLOBULINS, INTRAVENOUS; /defic permitted but consider also IMMUNOLOGIC DEFICIENCY SYNDROMES ; /ther use: consider also IMMUNOGLOBULIN THERAPY see IMMUNIZATION, PASSIVE; allotypes = IMMUNOGLOBULIN ALLOTYPES or specifics |
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PO poisoning RE radiation effects TO toxicity TU therapeutic use UL ultrastructure UR urine |
| Pharm Action: |
Immunologic Factors |
| Previous Indexing: |
Gamma Globulins (1966-1969) |
| Public MeSH Note: | 72; IMMUNE SERUM GLOBULIN was heading 1965; GLOBULINS, IMMUNE & IMMUNE GLOBULINS were see IMMUNOGLOBULINS, INTRAVENOUS 1992-93 |
| Online Note: | use IMMUNOGLOBULINS, INTRAVENOUS to search GLOBULINS, IMMUNE& IMMUNE GLOBULINS 1992-93 |
| History Note: | 72(70); IMMUNE SERUM GLOBULIN was heading 1965; GLOBULINS, IMMUNE & IMMUNE GLOBULINS were see IMMUNOGLOBULINS, INTRAVENOUS 1992-93 |
| Related: |
Immunity
MeSH Paraproteinemias MeSH |
| DeCS ID: | 22210 |
| Unique ID: | D007136 |
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents |
| Date Established: | 1972/01/01 |
| Date of Entry: | 1999/01/01 |
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
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Immunoglobulins
- Preferred
| Concept UI |
M0011122 |
| Scope note | Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. |
| Preferred term | Immunoglobulins |
| Entry term(s) |
Globulin, Immune Globulins, Immune Immune Globulin Immune Globulins Immunoglobulin |
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