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Descriptor English: Fibronectins
Descriptor Spanish: Fibronectinas
Descriptor fibronectinas
Entry term(s) fibronectina
globulinas insolubles en frío
proteínas LETS
Scope note: Glicoproteínas que se encuentran en la superficie de las células, particularmente en las estructuras fibrilares. Las proteínas se pierden o reducen cuando estas células sufren transformaciones virales o químicas. Son altamente susceptibles a la proteolisis y son sustratos para el factor VIII activado de coagulación. Las formas presentes en el plasma se ldenominan globulinas insolubles en frío.
Descriptor Portuguese: Fibronectinas
Descriptor French: Fibronectines
Entry term(s): Cold Insoluble Globulins
Cold-Insoluble Globulins
Fibronectin
Globulins, Cold-Insoluble
Glycoprotein, Opsonic
LETS Proteins
Opsonic Glycoprotein
Opsonic alpha(2)SB Glycoprotein
Proteins, LETS
alpha 2 Surface Binding Glycoprotein
alpha 2-Surface Binding Glycoprotein
Tree number(s): D09.400.430.890.350
D12.776.377.715.390
D12.776.395.550.350
D12.776.543.550.350
D12.776.860.300.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005353
Scope note: Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
Annotation: extracellular matrix proteins; /biosyn /physiol permitted
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cryoglobulins (1966-1979)
Glycoproteins (1966-1979)
Membrane Proteins (1977-1979)
Public MeSH Note: 80
History Note: 80
Related: Receptors, Fibronectin MeSH
DeCS ID: 29414
Unique ID: D005353
NLM Classification: QU 55.3
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1979/02/21
Revision Date: 2005/06/30
Fibronectins - Preferred
Concept UI M0008450
Scope note Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
Preferred term Fibronectins
Entry term(s) Cold Insoluble Globulins
Cold-Insoluble Globulins
Fibronectin
Globulins, Cold-Insoluble
Glycoprotein, Opsonic
LETS Proteins
Opsonic Glycoprotein
Opsonic alpha(2)SB Glycoprotein
Proteins, LETS
alpha 2 Surface Binding Glycoprotein
alpha 2-Surface Binding Glycoprotein



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