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Descriptor English: RNA, Messenger
Descriptor Spanish: ARN Mensajero
Descriptor ARN mensajero
Entry term(s) ARN mensajero poliadenilatado
ARNm
ARNm no poliadenilatado
ARNm poli(A)+
ARNm poliadenilatado
RNA mensajero poliadenilatado
RNA poliadenilatado
RNAm
RNAm no poliadenilatado
RNAm poli(A)+
RNAm poliadenilatado
cola de poli(A)
mRNA
poli(A)+ RNAm
Scope note: Secuencias de ARN que funcionan como molde para la síntesis de proteínas. Los ARNm bacterianos generalmente son copias primarias, ya que no requieren de procesamiento postranscripcional. Los ARNm eucarióticos se sintetizan en el núcleo y deben exportarse hacia el citoplasma para la traducción. La mayoría de los ARNm de eucariotas tienen una secuencia de ácido poliadenílico en el extremo 3', conocida como cola de poli(A). La función de este extremo no se conoce con exactitud, pero es posible que intervenga en la exportación del ARNm maduro desdel el núcleo y que ayude a estabilizar algunas moléculas de ARNm al retardar su degradación en el citoplasma.
Descriptor Portuguese: RNA Mensageiro
Descriptor French: ARN messager
Entry term(s): Messenger RNA
Messenger RNA, Polyadenylated
Non Polyadenylated mRNA
Non-Polyadenylated mRNA
Poly(A) RNA
Poly(A) Tail
Poly(A)+ RNA
Poly(A)+ mRNA
Polyadenylated Messenger RNA
Polyadenylated RNA
Polyadenylated mRNA
RNA, Messenger, Polyadenylated
RNA, Polyadenylated
RNA, Polyadenylated Messenger
mRNA
mRNA, Non Polyadenylated
mRNA, Non-Polyadenylated
mRNA, Polyadenylated
Tree number(s): D13.444.735.544
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D012333
Scope note: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 65; NON-POLYADENYLATED MRNA was indexed under RNA, MESSENGER 1981-94; POLYADENYLATED MRNA & POLY(A) RNA were indexed under POLY A & RNA, MESSENGER 1980-94
Online Note: use RNA, MESSENGER (NM) to search MRNA, NON-POLYADENYLATED 1981-94, MRNA, POLYADENYLATED 1980-94, & POLY(A)+ RNA 1980-94
History Note: 65(64); MRNA, NON-POLYADENYLATED was NON-POLYADENYLATED MRNA (NM) 1981-94; MRNA, POLYADENYLATED was POLYADENYLATED MRNA (NM) 1980-94; POLY(A)+ RNA was SY to POLY(A) RNA (NM) 1980-94
DeCS ID: 22282
Unique ID: D012333
NLM Classification: QU 58.7
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05
RNA, Messenger - Preferred
Concept UI M0019167
Scope note RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Preferred term RNA, Messenger
Entry term(s) Messenger RNA
mRNA
RNA, Polyadenylated - Narrower
Concept UI M0019170
Preferred term RNA, Polyadenylated
Entry term(s) Poly(A) RNA
Poly(A)+ RNA
Polyadenylated RNA
Poly(A) Tail - Narrower
Concept UI M0019171
Preferred term Poly(A) Tail
mRNA, Non-Polyadenylated - Narrower
Concept UI M0019168
Preferred term mRNA, Non-Polyadenylated
Entry term(s) Non Polyadenylated mRNA
Non-Polyadenylated mRNA
mRNA, Non Polyadenylated
mRNA, Polyadenylated - Narrower
Concept UI M0019169
Preferred term mRNA, Polyadenylated
Entry term(s) Messenger RNA, Polyadenylated
Poly(A)+ mRNA
Polyadenylated Messenger RNA
Polyadenylated mRNA
RNA, Messenger, Polyadenylated
RNA, Polyadenylated Messenger



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