| Descriptor English: | Insulin-Like Growth Factor II | ||||||
| Descriptor Spanish: |
Factor II del Crecimiento Similar a la Insulina
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| Descriptor Portuguese: | Fator de Crescimento Insulin-Like II | ||||||
| Descriptor French: | Facteur de croissance IGF-II | ||||||
| Entry term(s): |
Factor, Multiplication-Stimulating IGF-2 IGF-II Insulin Like Growth Factor II Insulin Like Somatomedin Peptide II Insulin-Like Somatomedin Peptide II Multiplication Stimulating Activity Multiplication Stimulating Factor Multiplication-Stimulating Activity Multiplication-Stimulating Factor Somatomedin A Somatomedin MSA |
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| Tree number(s): |
D12.644.276.937.420 D12.776.124.862.425 D12.776.467.937.420 D23.529.937.420 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D007335 | ||||||
| Scope note: | A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | 67763-97-7 | ||||||
| CAS Type 1 Name: | Insulin-like growth factor II | ||||||
| Previous Indexing: |
Blood Proteins (1966-1985) Growth Substances (1966-1985) Insulin (1966-1985) Peptides (1966-1985) Somatomedins (1973-1985) Sulfation Factor (1971-1972) |
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| Public MeSH Note: | 1991; see SOMATOMEDINS 1986-1990; SOMATOMEDIN A was indexed under INSULIN-LIKE GROWTH FACTOR II 1980-2004 |
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| History Note: | 1991(1986) |
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| Related: |
Receptor, IGF Type 1
MeSH Receptor, IGF Type 2 MeSH | ||||||
| DeCS ID: | 22313 | ||||||
| Unique ID: | D007335 | ||||||
| NLM Classification: | QU 107 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1985/04/25 | ||||||
| Revision Date: | 2006/07/05 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Insulin-Like Growth Factor II
- Preferred
| Concept UI |
M0011435 |
| Scope note | A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults. |
| Preferred term | Insulin-Like Growth Factor II |
| Entry term(s) |
Factor, Multiplication-Stimulating IGF-2 IGF-II Insulin Like Growth Factor II Insulin Like Somatomedin Peptide II Insulin-Like Somatomedin Peptide II Multiplication Stimulating Activity Multiplication Stimulating Factor Multiplication-Stimulating Activity Multiplication-Stimulating Factor Somatomedin A Somatomedin MSA |
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