Search
Descriptor English: Insulin-Like Growth Factor II
Descriptor Spanish: Factor II del Crecimiento Similar a la Insulina
Descriptor factor II de crecimiento insulinoide
Entry term(s) IGF-II
actividad estimulante de la multiplicación
somatomedina MSA
Scope note: Péptido neutro bien caracterizado. Se cree que es segregado por el HIGADO y que circula en la SANGRE. Tiene actividades de regulación de crecimiento, similares a la insulina y mitogénica. Este factor de crecimiento tiene una importante dependencia, pero no absoluta, de la SOMATOTROPINA. Se cree que es un factor de crecimiento fetal fundamental, a diferencia del FACTOR I DEL CRECIMIENTO INSULINOIDE, que es un factor de crecimiento fundamental en los adultos.
Descriptor Portuguese: Fator de Crescimento Insulin-Like II
Descriptor French: Facteur de croissance IGF-II
Entry term(s): Factor, Multiplication-Stimulating
IGF-2
IGF-II
Insulin Like Growth Factor II
Insulin Like Somatomedin Peptide II
Insulin-Like Somatomedin Peptide II
Multiplication Stimulating Activity
Multiplication Stimulating Factor
Multiplication-Stimulating Activity
Multiplication-Stimulating Factor
Somatomedin A
Somatomedin MSA
Tree number(s): D12.776.124.862.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007335
Scope note: A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 67763-97-7
CAS Type 1 Name: Insulin-like growth factor II
Previous Indexing: Blood Proteins (1966-1985)
Growth Substances (1966-1985)
Insulin (1966-1985)
Peptides (1966-1985)
Somatomedins (1973-1985)
Sulfation Factor (1971-1972)
Public MeSH Note: 1991; see SOMATOMEDINS 1986-1990; SOMATOMEDIN A was indexed under INSULIN-LIKE GROWTH FACTOR II 1980-2004
History Note: 1991(1986)
Related: Receptor, IGF Type 1 MeSH
Receptor, IGF Type 2 MeSH
DeCS ID: 22313
Unique ID: D007335
NLM Classification: QU 107
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1985/04/25
Revision Date: 2006/07/05
Insulin-Like Growth Factor II - Preferred
Concept UI M0011435
Scope note A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
Preferred term Insulin-Like Growth Factor II
Entry term(s) Factor, Multiplication-Stimulating
IGF-2
IGF-II
Insulin Like Growth Factor II
Insulin Like Somatomedin Peptide II
Insulin-Like Somatomedin Peptide II
Multiplication Stimulating Activity
Multiplication Stimulating Factor
Multiplication-Stimulating Activity
Multiplication-Stimulating Factor
Somatomedin A
Somatomedin MSA



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey