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Descriptor English: Gossypol
Descriptor Spanish: Gosipol
Descriptor gosipol
Scope note: Sesquiterpeno dimérico que se encuentra en la semilla del algodón (GOSSYPIUM). El isómero (-) es activo como anticonceptivo masculino (AGENTES ANTICONCEPTIVOS MASCULINOS) mientras que con el isómero (+) se asocian síntomas de toxicidad.
Descriptor Portuguese: Gossipol
Descriptor French: Gossypol
Entry term(s): Dipotassium Salt, Gossypol
Gossypol Dipotassium Salt
Gossypol Sodium Salt
Gossypol, (+)-Isomer
Gossypol, (+-)-Isomer
Gossypol, (-)-Isomer
Sodium Salt, Gossypol
Tree number(s): D02.455.849.765.444
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006072
Scope note: A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Contraceptive Agents, Male
Registry Number: KAV15B369O
CAS Type 1 Name: (2,2'-Binaphthalene)-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-
Related: Cottonseed Oil MeSH
DeCS ID: 22484
Unique ID: D006072
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Gossypol - Preferred
Concept UI M0009556
Scope note A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.
Preferred term Gossypol
Gossypol, (+-)-Isomer - Related but not broader or narrower
Concept UI M0330225
Preferred term Gossypol, (+-)-Isomer
Gossypol Sodium Salt - Narrower
Concept UI M0330224
Preferred term Gossypol Sodium Salt
Entry term(s) Sodium Salt, Gossypol
Gossypol, (+)-Isomer - Narrower
Concept UI M0330223
Preferred term Gossypol, (+)-Isomer
Gossypol, (-)-Isomer - Narrower
Concept UI M0330226
Preferred term Gossypol, (-)-Isomer
Gossypol Dipotassium Salt - Narrower
Concept UI M0330222
Preferred term Gossypol Dipotassium Salt
Entry term(s) Dipotassium Salt, Gossypol



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