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Descriptor English: O-(Chloroacetylcarbamoyl)fumagillol
Descriptor Spanish: O-(Cloroacetilcarbamoil) Fumagilol
Descriptor O-(cloroacetilcarbamoil)fumagilol
Entry term(s) 5-metoxi-4-(2-metil-3-(3-metil-2-butenil)oxiranil)-1-oxaspiro(2,5)oct-6-il(cloroacetil) carbamato
AGM 1470
AGM-1470
AGM1470
TNP 470
TNP-470
TNP470
caplostatin
Scope note: Análogo semisintético de la fumagilina (un antibiótico sesquiterpénico ciclohexánico aislado a partir de ASPERGILLUS FUMIGATUS) que inhibe la angiogénesis.
Descriptor Portuguese: O-(Cloroacetilcarbamoil)fumagilol
Descriptor French: O-(Chloroacetylcarbamoyl)fumagillol
Entry term(s): 5-Methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2,5)oct-6-yl(chloroacetyl) carbamate
AGM 1470
AGM-1470
AGM1470
Caplostatin
TNP 470
TNP-470
TNP470
Tree number(s): D02.455.426.392.368.367.763
D02.455.849.765.597
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077609
Scope note: Semisynthetic analog of fumagillin (a cyclohexane-sesquiterpene antibiotic isolated from ASPERGILLUS FUMIGATUS) that inhibits angiogenesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Angiogenesis Inhibitors
Registry Number: X47GR46481
Public MeSH Note: 2019; O-(CHLOROACETYLCARBAMOYL)FUMAGILLOL was indexed under CYCLOHEXANES and SESQUITERPENES 1991-2018
History Note: 2019 (1991)
DeCS ID: 57712
Unique ID: D000077609
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
O-(Chloroacetylcarbamoyl)fumagillol - Preferred
Concept UI M0182531
Scope note Semisynthetic analog of fumagillin (a cyclohexane-sesquiterpene antibiotic isolated from ASPERGILLUS FUMIGATUS) that inhibits angiogenesis.
Preferred term O-(Chloroacetylcarbamoyl)fumagillol
Entry term(s) 5-Methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2,5)oct-6-yl(chloroacetyl) carbamate
AGM 1470 - Narrower
Concept UI M0182534
Preferred term AGM 1470
Entry term(s) AGM-1470
AGM1470
TNP 470 - Narrower
Concept UI M0182532
Preferred term TNP 470
Entry term(s) TNP-470
TNP470
Caplostatin - Narrower
Concept UI M0499482
Preferred term Caplostatin



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