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Descriptor English: beta-Endorphin
Descriptor Spanish: betaendorfina
Descriptor beta-endorfina
Entry term(s) endorfina beta
lipotropina 61-91
Scope note: Péptido de 31 aminoácidos que constituye el fragmento C-terminal de la LIPOTROPINA BETA. Actúa en los RECEPTORES DE OPIOIDES y tiene acción analgésica. Sus cuatro primeros aminoácidos del extremo N-terminal son idénticos a la secuencia tetrapeptídica de la ENCEFALINA METIONINA y la ENCEFALINA LEUCINA.
Descriptor Portuguese: beta-Endorfina
Descriptor French: bêta-Endorphine
Entry term(s): Endorphin, beta
beta Endorphin
beta-Endorphin (1-31)
Tree number(s): D06.472.699.327.935.239
D06.472.699.631.525.600.239
D12.644.400.400.935.239
D12.644.400.575.241.080
D12.644.548.365.935.239
D12.644.548.691.525.690.239
D12.776.631.650.405.935.239
D12.776.631.650.575.241.080
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001615
Scope note: A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPTORS and is an analgesic. Its first four amino acids at the N-terminal are identical to the tetrapeptide sequence of METHIONINE ENKEPHALIN and LEUCINE ENKEPHALIN.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Neurotransmitter Agents
Registry Number: 60617-12-1
Previous Indexing: Endorphins (1978-1987)
Peptides (1966-1977)
Public MeSH Note: 1988; BETA-ENDORPHIN (1-31) was indexed under BETA-ENDORPHIN & PEPTIDE FRAGMENTS 1985-2006
History Note: 1988 (1985)
DeCS ID: 22846
Unique ID: D001615
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1987/05/04
Revision Date: 2015/11/23
beta-Endorphin - Preferred
Concept UI M0002414
Scope note A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPTORS and is an analgesic. Its first four amino acids at the N-terminal are identical to the tetrapeptide sequence of METHIONINE ENKEPHALIN and LEUCINE ENKEPHALIN.
Preferred term beta-Endorphin
Entry term(s) Endorphin, beta
beta Endorphin
beta-Endorphin (1-31)



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