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Descriptor English: Pro-Opiomelanocortin
Descriptor Spanish: Proopiomelanocortina
Descriptor Portuguese: Pró-Opiomelanocortina
Descriptor French: Pro-opiomélanocortine
Entry term(s): ACTH Endorphin Precursor
ACTH beta Lipotropin Precursor
ACTH-Endorphin Precursor
ACTH-beta-Lipotropin Precursor
Corticotropin beta Lipotropin Precursor
Corticotropin-beta-Lipotropin Precursor
Endorphin ACTH Precursor
Endorphin-ACTH Precursor
Opiocortin
POMC
Pre POMC
Pre pro opiocortin
Pre-POMC
Pre-pro-opiocortin
Preproopiomelanocortin
Pro ACTH Endorphin
Pro Opio Melanocortin
Pro Opiocortin
Pro Opiomelanocortin
Pro-ACTH-Endorphin
Pro-Opio-Melanocortin
Pro-Opiocortin
Proopiocortin
Proopiomelanocortin
Tree number(s): D06.472.699.327.935
D06.472.699.631.525.600
D12.644.400.400.935
D12.644.548.365.935
D12.644.548.691.525.690
D12.776.631.650.405.935
D12.776.811.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011333
Scope note: A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: 66796-54-1
CAS Type 1 Name: Opiomelanocortin, pro-
Previous Indexing: Pituitary Hormones, Anterior (1966-1984)
Protein Precursors (1973-1984)
Public MeSH Note: 1985; PRE-PRO-OPIOCORTIN was indexed under PRO-OPIOMELANOCORTIN & PROTEIN PRECURSORS 1980-2007; OPIOCORTIN was indexed under PRO-OPIOMELANOCORTIN 1987-2007
History Note: 1985
DeCS ID: 21050
Unique ID: D011333
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1985/01/01
Date of Entry: 1984/05/30
Revision Date: 2015/11/24
Pro-Opiomelanocortin - Preferred
Concept UI M0017593
Scope note A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
Preferred term Pro-Opiomelanocortin
Entry term(s) ACTH Endorphin Precursor
ACTH beta Lipotropin Precursor
ACTH-Endorphin Precursor
ACTH-beta-Lipotropin Precursor
Corticotropin beta Lipotropin Precursor
Corticotropin-beta-Lipotropin Precursor
Endorphin ACTH Precursor
Endorphin-ACTH Precursor
POMC
Pro ACTH Endorphin
Pro Opio Melanocortin
Pro Opiocortin
Pro Opiomelanocortin
Pro-ACTH-Endorphin
Pro-Opio-Melanocortin
Pro-Opiocortin
Proopiocortin
Proopiomelanocortin
Preproopiomelanocortin - Narrower
Concept UI M0084908
Preferred term Preproopiomelanocortin
Entry term(s) Pre POMC
Pre pro opiocortin
Pre-POMC
Pre-pro-opiocortin
Opiocortin - Narrower
Concept UI M0145713
Preferred term Opiocortin



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