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Descriptor English: Drug Carriers
Descriptor Spanish: Portadores de Fármacos
Descriptor portadores de fármacos
Entry term(s) portadores de medicamentos
transportadores de fármacos
Scope note: Formas a las que se incorporan sustancias con el fin de mejorar la liberación y la efectividad de los fármacos. Los portadores de fármacos se utilizan en los sistemas de liberación de fármacos como en la tecnología de liberación controlada para prolongar las acciones del fármaco in vivo, disminuir su metabolismo y su toxicidad. También se utilizan los portadores en diseños para aumentar la efectividad de la liberación del fármaco en los sitios diana de las acciones farmacológicas. Se han empleado liposomas, microesferas de albúmina, polímeros sintéticos solubles, complejos de ADN, conjugados de proteína-fármaco y hematíes portadores entre otros como portadoras de fármacos biodegradables.
Descriptor Portuguese: Portadores de Fármacos
Descriptor French: Vecteurs de médicaments
Entry term(s): Drug Carrier
Tree number(s): D26.255.260
E02.319.300.380
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004337
Scope note: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Annotation: coord with specific drug
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Previous Indexing: Delayed-Action Preparations (1966-1987)
Drugs (1966-1987)
Public MeSH Note: 88
History Note: 88
Related: Magnetic Iron Oxide Nanoparticles MeSH
DeCS ID: 22882
Unique ID: D004337
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1987/05/04
Revision Date: 2013/07/09
Drug Carriers - Preferred
Concept UI M0006822
Scope note Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
Preferred term Drug Carriers
Entry term(s) Drug Carrier



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