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Descriptor English: Abuse-Deterrent Formulations
Descriptor Spanish: Formulaciones Disuasorias del Abuso
Descriptor formulaciones disuasorias del abuso
Entry term(s) formulación disuasoria del abuso
Scope note: Formulaciones de medicamentos o sistemas de administración dirigidos a disuadir del abuso de SUSTANCIAS CONTROLADAS. Pueden incluir barreras físicas para impedir la masticación o la trituración del medicamento; barreras químicas para evitar la extracción de los ingredientes psicoactivos; combinaciones de agonistas y antagonistas para reducir la euforia asociada al abuso; aversión, combinación de las sustancias controladas con otras que producirán un efecto desagradable si el paciente manipula la forma de administración o excede la dosis recomendada; sistemas de administración resistentes al abuso, como los implantes, o combinaciones de estos métodos.
Descriptor Portuguese: Formulações de Dissuasão de Abuso
Descriptor French: Formulations dissuadant les abus
Entry term(s): Abuse Deterrent Formulation
Abuse Deterrent Formulations
Abuse-Deterrent Formulation
Formulation, Abuse-Deterrent
Formulations, Abuse-Deterrent
Tree number(s): D26.255.075
D27.505.696.034
D27.505.696.663.850.007
D27.505.954.427.005
E02.319.300.127
E05.916.250.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000075162
Scope note: Drug formulations or delivery systems intended to discourage the abuse of CONTROLLED SUBSTANCES. These may include physical barriers to prevent chewing or crushing the drug; chemical barriers that prevent extraction of psychoactive ingredients; agonist-antagonist combinations to reduce euphoria associated with abuse; aversion, where controlled substances are combined with others that will produce an unpleasant effect if the patient manipulates the dosage form or exceeds the recommended dose; delivery systems that are resistant to abuse such as implants; or combinations of these methods.
Allowable Qualifiers: AE adverse effects
CL classification
EC economics
ES ethics
HI history
IS instrumentation
MO mortality
MT methods
NU nursing
PX psychology
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Public MeSH Note: 2018
History Note: 2018
Related: Drug Compounding MeSH
DeCS ID: 57149
Unique ID: D000075162
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/22
Abuse-Deterrent Formulations - Preferred
Concept UI M000629657
Scope note Drug formulations or delivery systems intended to discourage the abuse of CONTROLLED SUBSTANCES. These may include physical barriers to prevent chewing or crushing the drug; chemical barriers that prevent extraction of psychoactive ingredients; agonist-antagonist combinations to reduce euphoria associated with abuse; aversion, where controlled substances are combined with others that will produce an unpleasant effect if the patient manipulates the dosage form or exceeds the recommended dose; delivery systems that are resistant to abuse such as implants; or combinations of these methods.
Preferred term Abuse-Deterrent Formulations
Entry term(s) Abuse Deterrent Formulation
Abuse Deterrent Formulations
Abuse-Deterrent Formulation
Formulation, Abuse-Deterrent
Formulations, Abuse-Deterrent



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