Search
Descriptor English: DNA Restriction-Modification Enzymes
Descriptor Spanish: Enzimas de Restricción-Modificación del ADN
Descriptor Portuguese: Enzimas de Restrição-Modificação do DNA
Descriptor French: Enzymes de restriction-modification de l'ADN
Entry term(s): DNA Restriction Modification Enzymes
Enzymes, DNA Restriction-Modification
Modification Systems, Restriction
Restriction Modification Systems
Restriction-Modification Enzymes, DNA
Restriction-Modification Systems
Systems, Restriction Modification
Systems, Restriction-Modification
Tree number(s): D08.811.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015280
Scope note: Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.
Annotation:
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA Restriction Enzymes (1975-1988)
Methyltransferases (1971-1988)
Public MeSH Note: 89
History Note: 89
Entry Version: RESTRICT MOD ENZYMES
DeCS ID: 23619
Unique ID: D015280
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/23
Revision Date: 2003/07/09
DNA Restriction-Modification Enzymes - Preferred
Concept UI M0023522
Scope note Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.
Preferred term DNA Restriction-Modification Enzymes
Entry term(s) DNA Restriction Modification Enzymes
Enzymes, DNA Restriction-Modification
Modification Systems, Restriction
Restriction Modification Systems
Restriction-Modification Enzymes, DNA
Restriction-Modification Systems
Systems, Restriction Modification
Systems, Restriction-Modification



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey