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Descriptor English: Glycoprotein Hormones, alpha Subunit
Descriptor Spanish: Hormonas Glicoproteicas de Subunidad alfa
Descriptor subunidad alfa de las hormonas glicoproteicas
Entry term(s) subunidad alfa de la FSH
subunidad alfa de la LH
subunidad alfa de la TSH
subunidad alfa de la hormona estimulante de la tiroides
subunidad alfa de la hormona foliculoestimulante
subunidad alfa de la hormona luteinizante
subunidad alfa de la tirotropina
subunidad alfa de las hormonas glicoproteicas hipofisarias
Scope note: Cadena alfa de las hormonas glicoproteicas hipofisarias (TIROTROPINA, HORMONA FOLICULOESTIMULANTE, HORMONA LUTEINIZANTE) y de la GONADOTROPINA CORIÓNICA placentaria. En una misma especie, las subunidades alfa de estas cuatro hormonas son idénticas; las características funcionales distintivas de esas hormonas glicoproteicas están determinadas por las distintas subunidades beta. Ambas subunidades, heterodímeros unidos no covalentemente, son necesarias para que la actividad biológica sea completa.
Descriptor Portuguese: Subunidade alfa de Hormônios Glicoproteicos
Descriptor French: Sous-unité alpha des hormones glycoprotéiques
Entry term(s): ASGPH
Chorionic Gonadotropin, alpha
Chorionic Gonadotropin, alpha Subunit
Common alpha Subunit Glycoprotein Hormones
FSH alpha
FSH, alpha Subunit
FSH-alpha
Follicle Stimulating Hormone, alpha Subunit
Follicle-Stimulating Hormone, alpha Subunit
Glycoprotein Hormones, alpha Chain
Glycoprotein Hormones, alpha Polypeptide
LH, alpha Subunit
Luteinizing Hormone, alpha Subunit
Lutotropin alpha
Lutotropin-alpha
Pituitary Glycoprotein Hormone, alpha Subunit
TSH alpha
TSH, alpha Subunit
TSH-alpha
Thyroid Stimulating Hormone, alpha Subunit
Thyroid-Stimulating Hormone, alpha Subunit
Thyrotropin alpha Subunit
Tree number(s): D06.472.699.322.326.562
D06.472.699.322.576.288.750
D06.472.699.322.576.463.249
D06.472.699.631.525.343.288.750
D06.472.699.631.525.343.463.249
D06.472.699.631.525.883.249
D06.472.699.649.367.562
D12.644.548.691.525.343.288.750
D12.644.548.691.525.343.463.249
D12.644.548.691.525.883.249
D12.644.548.726.367.562
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015292
Scope note: The alpha chain of pituitary glycoprotein hormones (THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE) and the placental CHORIONIC GONADOTROPIN. Within a species, the alpha subunits of these four hormones are identical; the distinct functional characteristics of these glycoprotein hormones are determined by the unique beta subunits. Both subunits, the non-covalently bound heterodimers, are required for full biologic activity.
Annotation: coord with THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE; or CHORIONIC GONADOTROPIN if particularly discussed
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: FSH (1972-1988)
Gonadotropins, Chorionic (1972-1988)
Gonadotropins, Pituitary (1972-1988)
LH (1972-1988)
Menotropins (1973-1988)
Pituitary Hormones, Anterior (1972-1988)
Thyrotropin (1972-1988)
Public MeSH Note: 1989
History Note: 1989
Entry Version: GPHAS
DeCS ID: 23658
Unique ID: D015292
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/24
Revision Date: 2011/06/24
Glycoprotein Hormones, alpha Subunit - Preferred
Concept UI M0023540
Scope note The alpha chain of pituitary glycoprotein hormones (THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE) and the placental CHORIONIC GONADOTROPIN. Within a species, the alpha subunits of these four hormones are identical; the distinct functional characteristics of these glycoprotein hormones are determined by the unique beta subunits. Both subunits, the non-covalently bound heterodimers, are required for full biologic activity.
Preferred term Glycoprotein Hormones, alpha Subunit
Entry term(s) ASGPH
Chorionic Gonadotropin, alpha
Chorionic Gonadotropin, alpha Subunit
Common alpha Subunit Glycoprotein Hormones
FSH alpha
FSH, alpha Subunit
FSH-alpha
Follicle Stimulating Hormone, alpha Subunit
Follicle-Stimulating Hormone, alpha Subunit
Glycoprotein Hormones, alpha Chain
Glycoprotein Hormones, alpha Polypeptide
LH, alpha Subunit
Luteinizing Hormone, alpha Subunit
Lutotropin alpha
Lutotropin-alpha
Pituitary Glycoprotein Hormone, alpha Subunit
TSH alpha
TSH, alpha Subunit
TSH-alpha
Thyroid Stimulating Hormone, alpha Subunit
Thyroid-Stimulating Hormone, alpha Subunit
Thyrotropin alpha Subunit



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