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Descriptor English: Thyrotropin
Descriptor Spanish: Tirotropina
Descriptor tirotropina
Entry term(s) TSH
hormona estimulante de la tiroides
Scope note: Hormona glicoproteica segregada por la ADENOHIPÓFISIS. Estimula la GLÁNDULA TIROIDES mediante el aumento del transporte de yoduro, la síntesis y la liberación de las hormonas tiroideas (TIROXINA y TRIYODOTIRONINA). La tirotropina está formada por dos subunidades no covalentes (alfa y beta) unidas. En una especie, la subunidad alfa es común en las hormonas glicoproteicas hipofisarias (TSH, HORMONA LUTEINIZANTE y FSH), pero la subunidad beta es única y le confiere su especificidad biológica.
Descriptor Portuguese: Tireotropina
Descriptor French: Thyréostimuline
Entry term(s): Hormone, Thyroid-Stimulating
TSH (Thyroid Stimulating Hormone)
Thyreotropin
Thyroid Stimulating Hormone
Thyroid-Stimulating Hormone
Thyrotrophin
Tree number(s): D06.472.699.631.525.883
D12.644.548.691.525.883
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013972
Scope note: A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.
Annotation: for alpha subunit, coord with GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; THYROTROPIN, BETA SUBUNIT is also available
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 9002-71-5
CAS Type 1 Name: Thyrotropin
Related: Receptors, Thyrotropin MeSH
DeCS ID: 22697
Unique ID: D013972
NLM Classification: WK 515
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2006/07/05
Thyrotropin - Preferred
Concept UI M0021496
Scope note A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.
Preferred term Thyrotropin
Entry term(s) Hormone, Thyroid-Stimulating
TSH (Thyroid Stimulating Hormone)
Thyreotropin
Thyroid Stimulating Hormone
Thyroid-Stimulating Hormone
Thyrotrophin



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