Search
Descriptor English: HLA-B Antigens
Descriptor Spanish: Antígenos HLA-B
Descriptor antígenos HLA-B
Entry term(s) antígeno HLA-B
Scope note: Antígenos de superficie del sistema principal de histocompatibilidad (HLA) humano de clase I codificado por más de 30 alelos detectables en el locus B del complejo mayor de histocompatibilidad, el más polimorfo de todas las especificidades del HLA. Varios de estos antígenos (p. ej., HLA-B27, HLA-B7, HLA-B8) están muy asociados a la predisposición a la artritis reumatoide y otros trastornos autoinmunitarios. Al igual que otros determinantes HLA de clase I, intervienen en la reactividad inmunitaria celular a los linfocitos T citolíticos.
Descriptor Portuguese: Antígenos HLA-B
Descriptor French: Antigènes HLA-B
Entry term(s): Antigen, HLA-B
Antigens, HLA B
Antigens, HLA-B
HLA B Antigen
HLA B Antigens
HLA-B
HLA-B Antigen
Tree number(s): D09.400.430.890.489.500
D12.776.395.550.489.500
D12.776.543.550.439.500
D23.050.301.500.100.500
D23.050.301.500.450.380
D23.050.705.552.100.500
D23.050.705.552.450.380
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015235
Scope note: Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
Annotation: general; prefer specifics
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: HLA Antigens (1975-1988)
Histocompatibility Antigens (1975-1981)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23670
Unique ID: D015235
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/14
Revision Date: 2020/05/27
HLA-B Antigens - Preferred
Concept UI M0023414
Scope note Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
Preferred term HLA-B Antigens
Entry term(s) Antigen, HLA-B
Antigens, HLA B
Antigens, HLA-B
HLA B Antigen
HLA B Antigens
HLA-B
HLA-B Antigen



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey