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Descriptor English: HLA-E Antigens
Descriptor Spanish: Antígenos HLA-E
Descriptor antígenos HLA-E
Entry term(s) HLA-E*0103
antígeno HLA E*0101
antígeno HLA-E 0103
antígeno HLA-E*0101
antígeno HLA-E*01:01
antígeno HLA-E*01:03
antígenos HLA E
Scope note: Antígenos de histocompatibilidad humana (HLA) de clase I codificados por genes situados en el locus E del cromosoma 6. Se unen a un subconjunto restringido de péptidos derivados de los péptidos líderes de otras moléculas de clase I. Intervienen principalmente en la regulación negativa de la actividad citolítica de las CÉLULAS NK y en la restricción de los LINFOCITOS T CD8-POSITIVOS no canónicos.
Descriptor Portuguese: Antígenos HLA-E
Descriptor French: Without translation
Entry term(s): HLA E Antigens
HLA E*0101 antigen
HLA-E 0103 antigen
HLA-E*0101 antigen
HLA-E*0103
HLA-E*01:01 antigen
HLA-E*01:03 antigen
Tree number(s): D09.400.430.890.489.850
D12.776.395.550.489.850
D12.776.543.550.439.850
D23.050.301.500.100.850
D23.050.705.552.100.850
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097625
Scope note: Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2024: HLA-E ANTIGEN was indexed under HISTOCOMPATIBILITY ANTIGENS CLASS I 1989-2023, and under HLA ANTIGENS 1988-1988
History Note: 2024 (1988)
DeCS ID: 60617
Unique ID: D000097625
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/14
HLA-E Antigens - Preferred
Concept UI M0158934
Scope note Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.
Preferred term HLA-E Antigens
Entry term(s) HLA E Antigens
HLA-E*01:01 antigen - Narrower
Concept UI M0509636
Preferred term HLA-E*01:01 antigen
Entry term(s) HLA E*0101 antigen
HLA-E*0101 antigen
HLA-E*01:03 antigen - Narrower
Concept UI M0507382
Preferred term HLA-E*01:03 antigen
Entry term(s) HLA-E 0103 antigen
HLA-E*0103



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