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Descriptor English: HLA-C Antigens
Descriptor Spanish: Antígenos HLA-C
Descriptor antígenos HLA-C
Scope note: Antígenos humanos de histocompatibilidad (HLA) de clase I codificados por un pequeño conjunto de genes estructurales del locus C del cromosoma 6. Su inmunogenicidad es significativamente menor que la de los determinantes HLA-A y HLA-B, y por tanto tienen poca importancia en la compatibilidad cruzada entre donante y receptor. Su papel fundamental es su asociación de alto riesgo con ciertas manifestaciones de enfermedades (p. ej., espondiloartritis, psoriasis, mieloma múltiple).
Descriptor Portuguese: Antígenos HLA-C
Descriptor French: Antigènes HLA-C
Entry term(s): Antigens, HLA C
Antigens, HLA-C
HLA C Antigens
HLA-C
Tree number(s): D09.400.430.890.489.600
D12.776.395.550.489.600
D12.776.543.550.439.600
D23.050.301.500.100.600
D23.050.301.500.450.390
D23.050.705.552.100.600
D23.050.705.552.450.390
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015236
Scope note: Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: HLA Antigens (1977-1988)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23671
Unique ID: D015236
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/14
Revision Date: 2016/07/01
HLA-C Antigens - Preferred
Concept UI M0023415
Scope note Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
Preferred term HLA-C Antigens
Entry term(s) Antigens, HLA C
Antigens, HLA-C
HLA C Antigens
HLA-C



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