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Descriptor English: Ofloxacin
Descriptor Spanish: Ofloxacino
Descriptor ofloxacin
Scope note: Fluoroquinolona sintética, un agente antibacteriano que inhibe la actividad de superenrollamiento de la ADN GIRASA bacteriana, impidiendo la REPLICACIÓN DEL ADN.
Descriptor Portuguese: Ofloxacino
Descriptor French: Ofloxacine
Tree number(s): D03.633.100.810.835.322.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015242
Scope note: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Registry Number: A4P49JAZ9H
CAS Type 1 Name: (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid
DeCS ID: 23786
Unique ID: D015242
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/16
Revision Date: 2016/05/31
Ofloxacine - Preferred
Concept UI M0023430
Preferred term Ofloxacine



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