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Descriptor English: Norfloxacin
Descriptor Spanish: Norfloxacino
Descriptor Portuguese: Norfloxacino
Descriptor French: Norfloxacine
Entry term(s): AM 0715
AM 715
AM-0715
AM-715
AM0715
MK 0366
MK 366
MK-0366
MK-366
MK0366
MK366
Noroxin
Tree number(s): D03.633.100.810.835.322.374
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009643
Scope note: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Topoisomerase II Inhibitors
Cytochrome P-450 CYP1A2 Inhibitors
Registry Number: N0F8P22L1P
CAS Type 1 Name: 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
Previous Indexing: Anti-Infective Agents (1966-1985)
Anti-Infective Agents, Urinary (1966-1985)
Nalidixic Acid (1966-1985)
Public MeSH Note: 86
History Note: 86
DeCS ID: 24350
Unique ID: D009643
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1985/06/06
Revision Date: 2017/05/24
Norfloxacin - Preferred
Concept UI M0014980
Scope note A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
Preferred term Norfloxacin
MK-0366 - Narrower
Concept UI M0353994
Preferred term MK-0366
Entry term(s) MK 0366
MK 366
MK-366
MK0366
MK366
Noroxin - Narrower
Concept UI M0501247
Preferred term Noroxin
AM-0715 - Narrower
Concept UI M0353993
Preferred term AM-0715
Entry term(s) AM 0715
AM 715
AM-715
AM0715



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