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Descriptor English: Eukaryotic Initiation Factor-1
Descriptor Spanish: Factor 1 Eucariótico de Iniciación
Descriptor factor de iniciación eucariótico 1
Entry term(s) EIF-1
factor EIF-1 de iniciación de péptidos
Scope note: Factor de iniciación eucariótico que se une a las subunidades ribosómicas 40S. Aunque inicialmente se consideró que era un factor "no esencial" para la iniciación de la transcripción eucariótica, en la actualidad se piensa que el factor de iniciación 1 eucariótico desempeña un papel importante en la localización de los RIBOSOMAS en el codón de iniciación del ARNm.
Descriptor Portuguese: Fator de Iniciação 1 em Eucariotos
Descriptor French: Facteur-1 d'initiation eucaryote
Entry term(s): EIF-1
Eukaryotic Initiation Factor 1
Eukaryotic Peptide Initiation Factor 1
Eukaryotic Peptide Initiation Factor-1
Peptide Initiation Factor EIF 1
Peptide Initiation Factor EIF-1
Tree number(s): D12.776.835.725.868.124
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015977
Scope note: A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a "non-essential" factor for eukaryotic transcription initiation, eukaryotic initiation factor-1 is now thought to play an important role in localizing RIBOSOMES at the initiation codon of MRNA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Peptide Initiation Factors (1978-1989)
Public MeSH Note: 2003; see EIF-1 1990-2002
History Note: 2003(1990)
DeCS ID: 24617
Unique ID: D015977
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/10/18
Revision Date: 2013/07/09
Eukaryotic Initiation Factor-1 - Preferred
Concept UI M0024412
Scope note A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a "non-essential" factor for eukaryotic transcription initiation, eukaryotic initiation factor-1 is now thought to play an important role in localizing RIBOSOMES at the initiation codon of MRNA.
Preferred term Eukaryotic Initiation Factor-1
Entry term(s) EIF-1
Eukaryotic Initiation Factor 1
Eukaryotic Peptide Initiation Factor 1
Eukaryotic Peptide Initiation Factor-1
Peptide Initiation Factor EIF 1
Peptide Initiation Factor EIF-1



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