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Descriptor English: Eukaryotic Initiation Factor-4F
Descriptor Spanish: Factor 4F Eucariótico de Iniciación
Descriptor factor de iniciación eucariótico 4F
Entry term(s) EIF-4F
factor EIF-4F de iniciación de péptidos
Scope note: Complejo trimérico del factor de iniciación de péptidos que se asocia con la estructura en caperuza del ARN en 5' del ARN (RNA CAPS) y desempeña una función esencial en la TRADUCCIÓN DEL ARNm. Está compuesto por el FACTOR DE INICIACIÓN EUCARIÓTICO 4A, el FACTOR DE INICIACIÓN EUCARIÓTICO 4E y el FACTOR DE INICIACIÓN EUCARIÓTICO 4G.
Descriptor Portuguese: Fator de Iniciação 4F em Eucariotos
Descriptor French: Facteur-4F d'initiation eucaryote
Entry term(s): EIF 4F
EIF-(iso)4F
EIF-4F
EIF4F
EIF4F Translation Initiation Complex
Eukaryotic Initiation Factor 4F
Eukaryotic Initiation Factor-(iso)4F
Initiation Factor-4F, Eukaryotic
Peptide Initiation Factor EIF 4F
Peptide Initiation Factor EIF-4F
Protein Initiation Factor EIF 4F
Protein Initiation Factor EIF-4F
Tree number(s): D12.776.664.962.750.374
D12.776.835.725.868.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039562
Scope note: A trimeric peptide initiation factor complex that associates with the 5' MRNA cap structure of RNA (RNA CAPS) and plays an essential role in MRNA TRANSLATION. It is composed of EUKARYOTIC INITIATION FACTOR-4A; EUKARYOTIC INITIATION FACTOR-4E; and EUKARYOTIC INITIATION FACTOR-4G.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Peptide Initiation Factors (1983-2002)
Public MeSH Note: 2003; EIF-4F (now EUKARYOTIC INITIATION FACTOR-4F) was indexed under PEPTIDE INITIATION FACTORS 1983-2003
History Note: 2003; use EUKARYOTIC INITIATION FACTOR-4F (NM) 1983-2003
DeCS ID: 37523
Unique ID: D039562
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2013/07/09
Eukaryotic Initiation Factor-4F - Preferred
Concept UI M0114953
Scope note A trimeric peptide initiation factor complex that associates with the 5' MRNA cap structure of RNA (RNA CAPS) and plays an essential role in MRNA TRANSLATION. It is composed of EUKARYOTIC INITIATION FACTOR-4A; EUKARYOTIC INITIATION FACTOR-4E; and EUKARYOTIC INITIATION FACTOR-4G.
Preferred term Eukaryotic Initiation Factor-4F
Entry term(s) EIF 4F
EIF-4F
EIF4F
EIF4F Translation Initiation Complex
Eukaryotic Initiation Factor 4F
Initiation Factor-4F, Eukaryotic
Peptide Initiation Factor EIF 4F
Peptide Initiation Factor EIF-4F
Protein Initiation Factor EIF 4F
Protein Initiation Factor EIF-4F
EIF-(iso)4F - Narrower
Concept UI M0114951
Scope note An isoform of eukaryotic initiation factor-4F found in plants.
Preferred term EIF-(iso)4F
Entry term(s) Eukaryotic Initiation Factor-(iso)4F



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