| Descriptor English: | HIV Envelope Protein gp120 | ||||||
| Descriptor Spanish: |
Proteína gp120 de Envoltorio del VIH
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| Descriptor Portuguese: | Proteína gp120 do Envelope de HIV | ||||||
| Descriptor French: | Protéine d'enveloppe gp120 du VIH | ||||||
| Entry term(s): |
Envelope Glycoprotein gp120, HIV HIV Envelope Glycoprotein gp120 HTLV III gp120 HTLV-III gp120 env Protein gp120, HIV gp120 Envelope Glycoprotein, HIV gp120(HIV) gp120, HTLV-III |
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| Tree number(s): |
D12.776.964.350.520.350 D12.776.964.775.325.164.249 D12.776.964.775.562.500.500 D12.776.964.970.880.325.164.249 D23.050.327.520.350 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015699 | ||||||
| Scope note: | External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Retroviridae Proteins (1986-1989) Viral Envelope Proteins (1983-1989) |
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| Public MeSH Note: | 90 |
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| History Note: | 90 |
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| Related: |
Peptide T
MeSH | ||||||
| DeCS ID: | 24717 | ||||||
| Unique ID: | D015699 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1990/01/01 | ||||||
| Date of Entry: | 1989/06/19 | ||||||
| Revision Date: | 2007/07/09 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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HIV Envelope Protein gp120
- Preferred
| Concept UI |
M0024082 |
| Scope note | External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV. |
| Preferred term | HIV Envelope Protein gp120 |
| Entry term(s) |
Envelope Glycoprotein gp120, HIV HIV Envelope Glycoprotein gp120 HTLV III gp120 HTLV-III gp120 env Protein gp120, HIV gp120 Envelope Glycoprotein, HIV gp120(HIV) gp120, HTLV-III |
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