Search
Descriptor English: Lambert-Eaton Myasthenic Syndrome
Descriptor Spanish: Síndrome Miasténico de Lambert-Eaton
Descriptor síndrome miasténico de Lambert-Eaton
Entry term(s) síndrome de Eaton-Lambert
Scope note: Enfermedad autoinmunitaria caracterizada por debilidad y fatigabilidad de los músculos proximales, particularmente de la cintura pélvica, extremidades inferiores, tronco, y cintura escapular. Etán relativamente preservados de los músculos bulbares y extraoculares. El CARCINOMA DE CÉLULAS PEQUEÑAS del pulmón es una afección asociada frecuentemente, aunque pueden asociarse otras neoplasias malignas y enfermedades autoinmunitarias. La debilidad muscular se produce por trastornos de la transmisión del impulso en la UNIÓN NEUROMUSCULAR. La disfunción del canal presináptico del calcio da lugar a reducción de la cantidad de acetilcolina liberada en respuesta a la estimulación del nervio. (Adams et al., Principles of Neurology, 6th ed, pp 1471)
Descriptor Portuguese: Síndrome Miastênica de Lambert-Eaton
Descriptor French: Syndrome myasthénique de Lambert-Eaton
Entry term(s): Eaton Lambert Myasthenic Syndrome
Eaton Lambert Syndrome
Eaton-Lambert Myasthenic Syndrome
Eaton-Lambert Myasthenic-Myopathic Syndrome
Eaton-Lambert Myopathic-Myasthenic Syndrome
Eaton-Lambert Myopathic-Myasthenic Syndromes
Eaton-Lambert Syndrome
Lambert Eaton Myasthenic Syndrome
Lambert Eaton Syndrome
Lambert-Eaton Myasthenic-Myopathic Syndrome
Lambert-Eaton Myasthenic-Myopathic Syndromes
Lambert-Eaton Myopathic-Myasthenic Syndrome
Lambert-Eaton Myopathic-Myasthenic Syndromes
Lambert-Eaton Syndrome
Myasthenic Myopathic Syndrome of Eaton Lambert
Myasthenic Myopathic Syndrome of Lambert Eaton
Myasthenic Syndrome, Eaton-Lambert
Myasthenic Syndrome, Lambert Eaton
Myasthenic Syndrome, Lambert-Eaton
Myasthenic-Myopathic Syndrome of Eaton-Lambert
Myasthenic-Myopathic Syndrome of Lambert-Eaton
Myopathic Myasthenic Syndrome of Eaton Lambert
Myopathic-Myasthenic Syndrome of Eaton-Lambert
Myopathic-Myasthenic Syndrome of Lambert-Eaton
Syndrome, Eaton-Lambert
Syndrome, Eaton-Lambert Myasthenic
Syndrome, Lambert-Eaton
Syndrome, Lambert-Eaton Myasthenic
Tree number(s): C04.588.614.550.500.225
C04.730.856.490.225
C10.114.656.150
C10.574.781.588.225
C10.668.758.725.150
C20.111.258.500.150
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015624
Scope note: An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Muscular Diseases (1967-1988)
Myasthenia Gravis (1980-1989)
Neuromuscular Diseases (1980-1989)
Neuromuscular Junction (1980-1986)
Public MeSH Note: 1990
History Note: 1990
DeCS ID: 24764
Unique ID: D015624
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/04/07
Revision Date: 2015/06/22
Lambert-Eaton Myasthenic Syndrome - Preferred
Concept UI M0023968
Scope note An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
Preferred term Lambert-Eaton Myasthenic Syndrome
Entry term(s) Eaton Lambert Myasthenic Syndrome
Eaton Lambert Syndrome
Eaton-Lambert Myasthenic Syndrome
Eaton-Lambert Myasthenic-Myopathic Syndrome
Eaton-Lambert Myopathic-Myasthenic Syndrome
Eaton-Lambert Myopathic-Myasthenic Syndromes
Eaton-Lambert Syndrome
Lambert Eaton Myasthenic Syndrome
Lambert Eaton Syndrome
Lambert-Eaton Myasthenic-Myopathic Syndrome
Lambert-Eaton Myasthenic-Myopathic Syndromes
Lambert-Eaton Myopathic-Myasthenic Syndrome
Lambert-Eaton Myopathic-Myasthenic Syndromes
Lambert-Eaton Syndrome
Myasthenic Myopathic Syndrome of Eaton Lambert
Myasthenic Myopathic Syndrome of Lambert Eaton
Myasthenic Syndrome, Eaton-Lambert
Myasthenic Syndrome, Lambert Eaton
Myasthenic Syndrome, Lambert-Eaton
Myasthenic-Myopathic Syndrome of Eaton-Lambert
Myasthenic-Myopathic Syndrome of Lambert-Eaton
Myopathic Myasthenic Syndrome of Eaton Lambert
Myopathic-Myasthenic Syndrome of Eaton-Lambert
Myopathic-Myasthenic Syndrome of Lambert-Eaton
Syndrome, Eaton-Lambert
Syndrome, Eaton-Lambert Myasthenic
Syndrome, Lambert-Eaton
Syndrome, Lambert-Eaton Myasthenic



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey