Search
Descriptor English: Myasthenia Gravis, Neonatal
Descriptor Spanish: Miastenia Gravis Neonatal
Descriptor miastenia gravis neonatal
Entry term(s) miastenia gravis antenatal
miastenia gravis neonatal transitoria
miastenia gravis prenatal
Scope note: Trastorno de la transmisión neuromuscular que se produce en una minoría de recién nacidos de madres con miastenia gravis. Por lo general, las caracerísticas clínicas se presentan al nacer o se desarrollan en los 3 primeros días de la vida y constan de hipotonía y afectación de la capacidad respiratoria, de succión y de deglución. Esta afección se asocia con la transferencia pasiva de anticuerpos contra los receptores de acetilcolina a través de la placenta. En la mayoría de los niños la debilidad miasténica desaparece (es decir, miastenia gravis neonatal transitoria) aunque este trastorno puede continuar infrecuentemente después del período neonatal (es decir, miastenia gravis neonatal persistente). (Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)
Descriptor Portuguese: Miastenia Gravis Neonatal
Descriptor French: Myasthénie congénitale
Entry term(s): Antenatal Myasthenia Gravis
Myasthenia Gravis, Antenatal
Myasthenia Gravis, Neonatal, Persistent
Myasthenia Gravis, Neonatal, Transient
Myasthenia Gravis, Persistent, Neonatal
Myasthenia Gravis, Transient, Neonatal
Neonatal Myasthenia Gravis
Neonatal Myasthenia Gravis, Persistent
Neonatal Myasthenia Gravis, Transient
Persistent Neonatal Myasthenia Gravis
Transient Neonatal Myasthenia Gravis
Tree number(s): C10.114.656.650
C10.668.758.725.650
C20.111.258.500.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020941
Scope note: A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Previous Indexing: Myasthenia Gravis (1965-1999)
Public MeSH Note: 2000
History Note: 2000
DeCS ID: 34210
Unique ID: D020941
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Myasthenia Gravis, Neonatal - Preferred
Concept UI M0328228
Scope note A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)
Preferred term Myasthenia Gravis, Neonatal
Entry term(s) Neonatal Myasthenia Gravis
Myasthenia Gravis, Neonatal, Persistent - Narrower
Concept UI M0335262
Preferred term Myasthenia Gravis, Neonatal, Persistent
Entry term(s) Myasthenia Gravis, Persistent, Neonatal
Neonatal Myasthenia Gravis, Persistent
Persistent Neonatal Myasthenia Gravis
Antenatal Myasthenia Gravis - Narrower
Concept UI M0335261
Preferred term Antenatal Myasthenia Gravis
Entry term(s) Myasthenia Gravis, Antenatal
Myasthenia Gravis, Neonatal, Transient - Narrower
Concept UI M0335263
Preferred term Myasthenia Gravis, Neonatal, Transient
Entry term(s) Myasthenia Gravis, Transient, Neonatal
Neonatal Myasthenia Gravis, Transient
Transient Neonatal Myasthenia Gravis



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey