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Descriptor English: Myasthenia Gravis
Descriptor Spanish: Miastenia Gravis
Descriptor miastenia gravis
Entry term(s) MG-MuSK
miastenia grave MuSK
miastenia grave con anticuerpos frente a MuSK
miastenia grave con anticuerpos frente a la tirosina-cinasa específica del músculo
miastenia grave por anticuerpos anti-MuSK
miastenia grave por anticuerpos frente a la tirosina-cinasa receptora específica del músculo
miastenia grave por anticuerpos frente al receptor tirosina-cinasa específico del músculo
Scope note: Trastorno de la transmisión neuromuscular que se caracteriza por debilidad fatigable de los músculos craneales y esqueléticos con títulos elevados de RECEPTORES DE ACETILCOLINA o autoanticuerpos frente a la tirosina-cinasa receptora específica del músculo (MuSK). Las manifestaciones clínicas pueden incluir debilidad muscular (oftalmoplejía externa asimétrica fluctuante, diplopía, ptosis palpebral y debilidad del cierre del ojo) y debilidad fatigable extraocular de los músculos faciales, bulbares y respiratorios, así como de los músculos proximales de las extremidades. La enfermedad puede permanecer limitada a los músculos oculares (miastenia ocular). El TIMOMA se asocia habitualmente a esta afección.
Descriptor Portuguese: Miastenia Gravis
Descriptor French: Myasthénie
Entry term(s): Anti MuSK Myasthenia Gravis
Anti-MuSK Myasthenia Gravis
Generalized Myasthenia Gravis
MuSK MG
MuSK Myasthenia Gravis
Muscle Specific Receptor Tyrosine Kinase Myasthenia Gravis
Muscle Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis
Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis
Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis
Myasthenia Gravis, Anti-MuSK
Myasthenia Gravis, Generalized
Myasthenia Gravis, MuSK
Myasthenia Gravis, Ocular
Ocular Myasthenia Gravis
Tree number(s): C04.588.614.550.500
C04.730.856.490
C10.114.656
C10.574.781.588
C10.668.758.725
C20.111.258.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009157
Scope note: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
Annotation: "myasthenia" unqualified in foreign titles is more often MYASTHENIA GRAVIS than MUSCLE WEAKNESS but check text; congenital: consider MYASTHENIC SYNDROMES, CONGENITAL or specifics
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
UR urine
VE veterinary
VI virology
Related: Thymus Hyperplasia MeSH
DeCS ID: 9349
Unique ID: D009157
NLM Classification: WE 555
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2019/04/15
Myasthenia Gravis - Preferred
Concept UI M0014279
Scope note A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
Preferred term Myasthenia Gravis
Myasthenia Gravis, Ocular - Narrower
Concept UI M0335256
Preferred term Myasthenia Gravis, Ocular
Entry term(s) Ocular Myasthenia Gravis
Myasthenia Gravis, Generalized - Narrower
Concept UI M0335255
Preferred term Myasthenia Gravis, Generalized
Entry term(s) Generalized Myasthenia Gravis
Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis - Narrower
Concept UI M000646708
Preferred term Muscle-Specific Receptor Tyrosine Kinase Myasthenia Gravis
Entry term(s) Anti MuSK Myasthenia Gravis
Anti-MuSK Myasthenia Gravis
MuSK MG
MuSK Myasthenia Gravis
Muscle Specific Receptor Tyrosine Kinase Myasthenia Gravis
Muscle Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis
Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis
Myasthenia Gravis, Anti-MuSK
Myasthenia Gravis, MuSK



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