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Descriptor English: Antithrombins
Descriptor Spanish: Antitrombinas
Descriptor antitrombinas
Entry term(s) antitrombina
antitrombina directa
antitrombinas directas
inhibidor directo de la trombina
Scope note: Familia de proteínas endógenas que pertenecen a la superfamilia de la serpina que neutraliza la acción de la trombina. Se han identificado seis antitrombinas naturales, a las que se ha designado con números romanos del I al VI. Las que mayor importancia parecen tener son la antitrombina I (ver FIBRINA) y ANTITROMBINA III.
Descriptor Portuguese: Antitrombinas
Descriptor French: Antithrombiniques
Tree number(s): D27.505.519.389.745.800.449
D27.505.954.502.119.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000991
Scope note: Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
Annotation: ANTITHROMBIN PROTEINS is also available
Allowable Qualifiers:
DeCS ID: 27917
Unique ID: D000991
NLM Classification: QV 193
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1967/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27



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