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Descriptor English: Serpins
Descriptor Spanish: Serpinas
Descriptor serpinas
Entry term(s) inhibidores de serpina peptidasa
inhibidores de serpina proteasa
serpina
superfamilia de las serpinas
Scope note: Familia de inhibidores de la serina-proteinasa que tienen una secuencia de aminoácidos y un mecanismo de inhibición similares, aunque difieren en su especificidad por las enzimas proteolíticas. Algunos miembros de la familia de las serpinas pueden ser sustratos, y no inhibidores, de las SERINA-ENDOPEPTIDASAS.
Descriptor Portuguese: Serpinas
Descriptor French: Serpines
Entry term(s): Inhibitors, Serpin Peptidase
Inhibitors, Serpin Protease
Peptidase Inhibitors, Serpin
Protease Inhibitors, Serpin
Serpin
Serpin Peptidase Inhibitors
Serpin Protease Inhibitors
Serpin Superfamily
Superfamily, Serpin
Tree number(s): D12.644.861
D12.776.872
D27.505.519.389.745.800.675
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015843
Scope note: A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Enzyme Inhibitors (1968-1978)
Protease Inhibitors (1979-1989)
Public MeSH Note: 90
History Note: 90
DeCS ID: 24875
Unique ID: D015843
NLM Classification: QU 143
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/05/26
Revision Date: 2020/05/27
Serpins - Preferred
Concept UI M0024262
Scope note A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
Preferred term Serpins
Entry term(s) Inhibitors, Serpin Peptidase
Inhibitors, Serpin Protease
Peptidase Inhibitors, Serpin
Protease Inhibitors, Serpin
Serpin
Serpin Peptidase Inhibitors
Serpin Protease Inhibitors
Serpin Superfamily - Broader
Concept UI M0024261
Scope note A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
Scope note A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
Preferred term Serpin Superfamily
Entry term(s) Superfamily, Serpin



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