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Descriptor English: Apazone
Descriptor Spanish: Apazona
Descriptor apazona
Entry term(s) azapropazona
Scope note: Agente antiinflamatorio utilizado en el tratamiento de la artritis reumatoide. También posee propiedades uricosúricas, por lo que se ha usado para el tratamiento de la gota.
Descriptor Portuguese: Apazona
Descriptor French: Azapropazone
Entry term(s): 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione
Apazone Dihydrate
Azapropazone
Dihydrate, Apazone
Prolixan
Rheumox
Tolyprin
Tree number(s): D03.383.931.190
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001032
Scope note: An anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Inflammatory Agents, Non-Steroidal
Uricosuric Agents
Registry Number: K2VOT966ZI
CAS Type 1 Name: 1H-Pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione, 5-(dimethylamino)-9-methyl-2-propyl-
Previous Indexing: Dimethylamines (1973-1974)
Malonates (1973-1974)
Triazines (1971-1974)
Public MeSH Note: 91; was see under TRIAZINES 1975-90
History Note: 91(75); was see under TRIAZINES 1975-90
DeCS ID: 27950
Unique ID: D001032
NLM Classification: QV 95
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2017/05/24
Apazone - Preferred
Concept UI M0001566
Scope note An anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout.
Preferred term Apazone
Entry term(s) 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione
Azapropazone
Prolixan - Narrower
Concept UI M0001567
Preferred term Prolixan
Tolyprin - Narrower
Concept UI M0440885
Preferred term Tolyprin
Apazone Dihydrate - Narrower
Concept UI M0330783
Preferred term Apazone Dihydrate
Entry term(s) Dihydrate, Apazone
Rheumox - Narrower
Concept UI M0440884
Preferred term Rheumox



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