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Descriptor English: Almitrine
Descriptor Spanish: Almitrina
Descriptor Portuguese: Almitrina
Descriptor French: Almitrine
Entry term(s): Almitrine Bis(methanesulfonate)
Almitrine Bismesylate
Almitrine Dimesylate
Almitrine Monomesylate
Monomesylate, Almitrine
Vectarion
Tree number(s): D03.383.606.130
D03.383.931.095
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015765
Scope note: A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Respiratory System Agents
Registry Number: 9A1222NBG4
CAS Type 1 Name: 1,3,5-Triazine-2,4-diamine, 6-(4-(bis(4-fluorophenyl)methyl)-1-piperazinyl)-N,N'-di-2-propenyl-
Previous Indexing: Analeptics (1966-1989)
Piperazines (1966-1989)
Public MeSH Note: 90
History Note: 90
DeCS ID: 24514
Unique ID: D015765
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1990/01/01
Date of Entry: 1989/05/15
Revision Date: 2017/05/24
Almitrine - Preferred
Concept UI M0024158
Scope note A respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.
Preferred term Almitrine
Almitrine Monomesylate - Narrower
Concept UI M0329452
Preferred term Almitrine Monomesylate
Entry term(s) Monomesylate, Almitrine
Vectarion - Narrower
Concept UI M0024160
Preferred term Vectarion
Almitrine Dimesylate - Narrower
Concept UI M0329453
Preferred term Almitrine Dimesylate
Entry term(s) Almitrine Bis(methanesulfonate)
Almitrine Bismesylate



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