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Descriptor English: Chlorpromazine
Descriptor Spanish: Clorpromazina
Descriptor clorpromacina
Scope note: Fenotiazina que es el prototipo de fármaco antipsicótico. Al igual que otras drogas de esta clase, las acciones antipsicóticas de la clorpromazina se cree que derivan de la adaptación del cerebro, a largo plazo, al bloqueo de los RECEPTORES DE DOPAMINA. La clorpromazina posee otras acciones y usos terapéuticos, incluso como antihemético y para el tratamiento del hipo rebelde.
Descriptor Portuguese: Clorpromazina
Descriptor French: Chlorpromazine
Entry term(s): Aminazine
Chlorazine
Chlordelazine
Chlorpromazine Hydrochloride
Contomin
Fenactil
Hydrochloride, Chlorpromazine
Largactil
Propaphenin
Thorazine
Tree number(s): D02.886.369.198
D03.633.300.783.198
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002746
Scope note: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antiemetics
Antipsychotic Agents
Dopamine Antagonists
Registry Number: U42B7VYA4P
CAS Type 1 Name: 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-
Public MeSH Note: /adverse effects /poisoning /toxicity were CHLORPROMAZINE TOXICOLOGY 1963-65
History Note: /adv eff-pois-tox was CHLORPROMAZINE TOXICOLOGY 1963-65
DeCS ID: 2798
Unique ID: D002746
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1960/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/05
Chlorpromazine - Preferred
Concept UI M0004198
Scope note The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Preferred term Chlorpromazine
Thorazine - Narrower
Concept UI M0004203
Preferred term Thorazine
Aminazine - Narrower
Concept UI M0418365
Preferred term Aminazine
Largactil - Narrower
Concept UI M0004199
Preferred term Largactil
Chlordelazine - Narrower
Concept UI M0354102
Preferred term Chlordelazine
Chlorpromazine Hydrochloride - Narrower
Concept UI M0363614
Preferred term Chlorpromazine Hydrochloride
Entry term(s) Hydrochloride, Chlorpromazine
Contomin - Narrower
Concept UI M0354101
Preferred term Contomin
Fenactil - Narrower
Concept UI M0354105
Preferred term Fenactil
Propaphenin - Narrower
Concept UI M0004202
Preferred term Propaphenin
Chlorazine - Narrower
Concept UI M0004201
Preferred term Chlorazine



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