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Descriptor in English: Multigene Family
Descriptor in Spanish: Familia de Multigenes
Descriptor in Portuguese: Família Multigênica
Descriptor in French: Famille multigénique
Entry term(s): Cluster, Gene
Clusters, Gene
Families, Multigene
Family, Multigene
Gene Cluster
Gene Clusters
Gene, Reiterated
Genes, Reiterated
Multigene Families
Reiterated Gene
Reiterated Genes
Tree number(s): G05.360.340.024.340.645
Scope note: A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
History Note: 97; was GENES, REITERATED 1987-96; MULTIGENE FAMILY was see GENES, REITERATED 1987-96
See also the descriptors: Gene Duplication MeSH
Genes, Duplicate MeSH
Repetitive Sequences, Nucleic Acid MeSH
DeCS UI: 28070
Descriptor UI: D005810
Date Established: 1987/01/01
Date of Entry: 1986/06/19
Revision Date: 2008/07/08
Multigene Family - Preferred
Concept UI M0009111
Scope note A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Preferred term Multigene Family
Entry term(s) Families, Multigene
Family, Multigene
Multigene Families
Genes, Reiterated - Narrower
Concept UI M0009112
Preferred term Genes, Reiterated
Entry term(s) Gene, Reiterated
Reiterated Gene
Reiterated Genes
Gene Clusters - Narrower
Concept UI M0009110
Preferred term Gene Clusters
Entry term(s) Cluster, Gene
Clusters, Gene
Gene Cluster



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