Descriptor in English: | Genes, Immunoglobulin |
Descriptor in Spanish: | Genes de Inmunoglobulinas |
Descriptor in Portuguese: | Genes de Imunoglobulinas |
Descriptor in French: | Gènes d'immunoglobuline |
Entry term(s): |
Gene, Ig Gene, Immunoglobulin Genes, Ig Ig Gene Ig Genes Immunoglobulin Gene Immunoglobulin Genes |
Tree number(s): |
G05.360.340.024.340.335 G12.500.299 |
Scope note: | Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity). |
Allowable Qualifiers: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
History Note: | 88 |
See also the descriptors: |
Immunogenetics
MeSH Immunoglobulin Allotypes MeSH Immunoglobulin Subunits MeSH Immunoglobulins MeSH |
DeCS UI: | 22903 |
Descriptor UI: | D005803 |
Date Established: | 1988/01/01 |
Date of Entry: | 1987/05/11 |
Revision Date: | 2008/07/08 |
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PHENOMENA AND PROCESSES
Genetic Phenomena [G05]Genetic Phenomena -
PHENOMENA AND PROCESSES
Immune System Phenomena [G12]Immune System Phenomena
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Genes, Immunoglobulin
- Preferred
Concept UI |
M0009095 |
Scope note | Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity). |
Preferred term | Genes, Immunoglobulin |
Entry term(s) |
Gene, Ig Gene, Immunoglobulin Genes, Ig Ig Gene Ig Genes Immunoglobulin Gene Immunoglobulin Genes |
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