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Descriptor English: Genes, Immunoglobulin
Descriptor Spanish: Genes de Inmunoglobulinas
Descriptor genes de las inmunoglobulinas
Entry term(s) genes de Ig
Scope note: Genes que codifican las distintas subunidades de las INMUNOGLOBULINAS, por ejemplo, los GENES DE LAS CADENAS LIGERAS DE LAS INMUNOGLOBULINAS y los GENES DE LAS CADENAS PESADAS DE LAS INMUNOGLOBULINAS. Los genes de las cadenas ligeras y pesadas están presentes como segmentos de genes en las células germinales. Los genes completos se crean cuando los segmentos se entremezclan y ensamblan (REORDENAMIENTO GÉNICO DEL LINFOCITO B) durante la maduración del LINFOCITO B. Los segmentos génicos de los genes de las cadenas ligeras y pesadas de las células germinales se simbolizan como V (variable), J (de unión) y C (constante). Los genes de las cadenas pesadas de las células germinales tienen un segmento D (diversidad) adicional.
Descriptor Portuguese: Genes de Imunoglobulinas
Descriptor French: Gènes d'immunoglobuline
Entry term(s): Gene, Ig
Gene, Immunoglobulin
Genes, Ig
Ig Gene
Ig Genes
Immunoglobulin Gene
Immunoglobulin Genes
Tree number(s): G05.360.340.024.340.335
G12.500.299
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005803
Scope note: Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Genes, Structural (1972-1987)
Immunoglobulins (1972-1987)
specific immunoglobulin chain or region (1975-1987)
Public MeSH Note: 88
History Note: 88
Entry Version: GENES IG
Related: Immunogenetics MeSH
Immunoglobulin Allotypes MeSH
Immunoglobulin Subunits MeSH
Immunoglobulins MeSH
DeCS ID: 22903
Unique ID: D005803
NLM Classification: QW 601
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1988/01/01
Date of Entry: 1987/05/11
Revision Date: 2008/07/08
Genes, Immunoglobulin - Preferred
Concept UI M0009095
Scope note Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
Preferred term Genes, Immunoglobulin
Entry term(s) Gene, Ig
Gene, Immunoglobulin
Genes, Ig
Ig Gene
Ig Genes
Immunoglobulin Gene
Immunoglobulin Genes



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