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Descriptor in English: Genes, Immunoglobulin
Descriptor in Spanish: Genes de Inmunoglobulinas
Descriptor in Portuguese: Genes de Imunoglobulinas
Descriptor in French: Gènes d'immunoglobuline
Entry term(s): Gene, Ig
Gene, Immunoglobulin
Genes, Ig
Ig Gene
Ig Genes
Immunoglobulin Gene
Immunoglobulin Genes
Tree number(s): G05.360.340.024.340.335
G12.500.299
Scope note: Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
History Note: 88
See also the descriptors: Immunogenetics MeSH
Immunoglobulin Allotypes MeSH
Immunoglobulin Subunits MeSH
Immunoglobulins MeSH
DeCS UI: 22903
Descriptor UI: D005803
Date Established: 1988/01/01
Date of Entry: 1987/05/11
Revision Date: 2008/07/08
Genes, Immunoglobulin - Preferred
Concept UI M0009095
Scope note Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
Preferred term Genes, Immunoglobulin
Entry term(s) Gene, Ig
Gene, Immunoglobulin
Genes, Ig
Ig Gene
Ig Genes
Immunoglobulin Gene
Immunoglobulin Genes



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