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Descriptor English: Lipopolysaccharides
Descriptor Spanish: Lipopolisacáridos
Descriptor lipopolisacáridos
Entry term(s) lipopolisacárido
Scope note: Polisacáridos que contienen lípidos; son endotoxinas e importantes antígenos específicos de grupo. Con frecuencia son derivados de la pared celular de bacterias gramnegativas e inducen la secreción de inmunoglobulinas. La molécula de los lipopolisácaridos constan de tres partes: el LÍPIDO A, el centro polisacáridoun y las cadenas O específicas (ANTÍGENOS O). Los lipopolisacáridos derivados de Escherichia coli son mitógenos de células B policlonales frecuentemente empleados en el laboratorio de inmunología. (Dorland, 28th ed)
Descriptor Portuguese: Lipopolissacarídeos
Descriptor French: Lipopolysaccharides
Entry term(s): Lipoglycans
Lipopolysaccharide
Tree number(s): D09.400.500
D09.698.718.450
D10.494
D23.050.161.616.525
D23.946.123.329.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008070
Scope note: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Annotation: oordinate with specific bacterium if pertinent
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Version: LPS
DeCS ID: 28155
Unique ID: D008070
NLM Classification: QU 83
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27
Lipopolysaccharides - Preferred
Concept UI M0012577
Scope note Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Preferred term Lipopolysaccharides
Entry term(s) Lipoglycans
Lipopolysaccharide



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